Swamikannu Bhuminathan, Umapathy Vidhya Rekha, Natarajan Prabhu M, Nandini M S, Queency Stylin Anin G S, Vimalarani V, Rajinikanth Suba
Department of Prosthodontics, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India.
Department of Public Health Dentistry, Thai Moogambigai Dental College and Hospital, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 5):S4248-S4253. doi: 10.4103/jpbs.jpbs_1250_24. Epub 2025 Jan 30.
Artemisia annua L., also referred to as sweet wormwood, sweet annie, sweet sagewort, and annual wormwood (Chinese: qngho), is a species of wormwood native to temperate Asia but naturalised worldwide. It is a member of the Asteraceae family. At the moment, Artemisia annua is the sources of artemisinin and semisynthetic artemisinin derivatives (including dihydroartemisinin, artesunate, artemether, and arteether) used in the development of malaria combination treatments (ACTs = Artemisinin-based combination therapy). Animal experiments have shown that similar chemicals can prevent tumor development and metastasis. Furthermore, there is no conclusive proof from human trials that the benefits seen in animal research extend to cancer patients. Experiences with malaria treatment indicate that artemisinin-based medicines are generally well-tolerated. This study highlights A. annua's traditional use and contemporary pharmacological research, bringing unique insights into the usage of A. annua in the treating a wide range of ailments.
青蒿,也被称为甜艾草、甜安妮、甜鼠尾草和一年生艾草(中文:青蒿),是一种原产于温带亚洲但已在全球归化的艾草。它是菊科植物的一员。目前,青蒿是青蒿素和半合成青蒿素衍生物(包括双氢青蒿素、青蒿琥酯、蒿甲醚和蒿乙醚)的来源,这些物质用于开发疟疾联合治疗药物(ACTs = 以青蒿素为基础的联合疗法)。动物实验表明,类似的化学物质可以预防肿瘤的发展和转移。此外,人体试验尚无确凿证据表明在动物研究中看到的益处也适用于癌症患者。疟疾治疗经验表明,以青蒿素为基础的药物通常耐受性良好。本研究突出了青蒿的传统用途和当代药理学研究,为青蒿在治疗多种疾病中的应用带来了独特见解。