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Unlocking the Therapeutic Benefits of Artemisia Annua: A Comprehensive Overview of its Medicinal Properties.解锁青蒿的治疗益处:对其药用特性的全面概述。
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 5):S4248-S4253. doi: 10.4103/jpbs.jpbs_1250_24. Epub 2025 Jan 30.
2
Differences in chemical constituents of Artemisia annua L from different geographical regions in China.中国不同地理区域青蒿化学成分的差异。
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Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin.黄花蒿次生代谢产物对癌细胞的细胞毒性活性与其指定活性成分青蒿素的比较。
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L. extracts inhibit the replication of SARS-CoV-2 and two of its variants.L提取物可抑制严重急性呼吸综合征冠状病毒2(SARS-CoV-2)及其两种变体的复制。
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本文引用的文献

1
First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin.首次比较青蒿草药茶和青蒿素的体外抗疟活性。
Trans R Soc Trop Med Hyg. 2012 Nov;106(11):696-700. doi: 10.1016/j.trstmh.2012.07.008. Epub 2012 Sep 15.
2
Extracts of Artemisia annua leaves and seeds mediate programmed cell death in Leishmania donovani.青蒿叶和种子提取物介导利什曼原虫的细胞程序性死亡。
J Med Microbiol. 2012 Dec;61(Pt 12):1709-1718. doi: 10.1099/jmm.0.049387-0. Epub 2012 Sep 6.
3
The flavonoids casticin and artemetin are poorly extracted and are unstable in an Artemisia annua tea infusion.二氢查尔酮和青蒿素在青蒿茶提取液中提取率低且不稳定。
Planta Med. 2012 Jun;78(10):1024-6. doi: 10.1055/s-0032-1314949. Epub 2012 Jun 6.
4
Ethnopharmacology in overdrive: the remarkable anti-HIV activity of Artemisia annua.超速行驶的民族药理学:青蒿素显著的抗 HIV 活性。
J Ethnopharmacol. 2012 Jun 14;141(3):854-9. doi: 10.1016/j.jep.2012.03.024. Epub 2012 Mar 24.
5
Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin.黄花蒿次生代谢产物对癌细胞的细胞毒性活性与其指定活性成分青蒿素的比较。
Phytomedicine. 2011 Aug 15;18(11):959-69. doi: 10.1016/j.phymed.2011.06.008. Epub 2011 Aug 9.
6
Simple and rapid micro-scale quantification of artemisinin in living Artemisia annua L. by improved gas chromatography with electron-capture detection.通过改进的带电子捕获检测的气相色谱法对活体黄花蒿中的青蒿素进行简单快速的微量定量分析。
Biomed Chromatogr. 2009 Oct;23(10):1101-7. doi: 10.1002/bmc.1230.
7
Artemisia species: From traditional medicines to modern antimalarials--and back again.蒿属植物:从传统药物到现代抗疟药——再回归传统
J Altern Complement Med. 2009 Feb;15(2):101-9. doi: 10.1089/acm.2008.0327.
8
Nutrient deficiency in the production of artemisinin, dihydroartemisinic acid, and artemisinic acid in Artemisia annua L.黄花蒿中青蒿素、二氢青蒿酸和青蒿酸生产中的营养缺乏
J Agric Food Chem. 2007 Mar 7;55(5):1686-94. doi: 10.1021/jf063017v. Epub 2007 Feb 13.
9
Effects of components of Artemisia annua on coccidia infections in chickens.青蒿成分对鸡球虫感染的影响。
Poult Sci. 1997 Aug;76(8):1156-63. doi: 10.1093/ps/76.8.1156.

解锁青蒿的治疗益处:对其药用特性的全面概述。

Unlocking the Therapeutic Benefits of Artemisia Annua: A Comprehensive Overview of its Medicinal Properties.

作者信息

Swamikannu Bhuminathan, Umapathy Vidhya Rekha, Natarajan Prabhu M, Nandini M S, Queency Stylin Anin G S, Vimalarani V, Rajinikanth Suba

机构信息

Department of Prosthodontics, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India.

Department of Public Health Dentistry, Thai Moogambigai Dental College and Hospital, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.

出版信息

J Pharm Bioallied Sci. 2024 Dec;16(Suppl 5):S4248-S4253. doi: 10.4103/jpbs.jpbs_1250_24. Epub 2025 Jan 30.

DOI:10.4103/jpbs.jpbs_1250_24
PMID:40061692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11888663/
Abstract

Artemisia annua L., also referred to as sweet wormwood, sweet annie, sweet sagewort, and annual wormwood (Chinese: qngho), is a species of wormwood native to temperate Asia but naturalised worldwide. It is a member of the Asteraceae family. At the moment, Artemisia annua is the sources of artemisinin and semisynthetic artemisinin derivatives (including dihydroartemisinin, artesunate, artemether, and arteether) used in the development of malaria combination treatments (ACTs = Artemisinin-based combination therapy). Animal experiments have shown that similar chemicals can prevent tumor development and metastasis. Furthermore, there is no conclusive proof from human trials that the benefits seen in animal research extend to cancer patients. Experiences with malaria treatment indicate that artemisinin-based medicines are generally well-tolerated. This study highlights A. annua's traditional use and contemporary pharmacological research, bringing unique insights into the usage of A. annua in the treating a wide range of ailments.

摘要

青蒿,也被称为甜艾草、甜安妮、甜鼠尾草和一年生艾草(中文:青蒿),是一种原产于温带亚洲但已在全球归化的艾草。它是菊科植物的一员。目前,青蒿是青蒿素和半合成青蒿素衍生物(包括双氢青蒿素、青蒿琥酯、蒿甲醚和蒿乙醚)的来源,这些物质用于开发疟疾联合治疗药物(ACTs = 以青蒿素为基础的联合疗法)。动物实验表明,类似的化学物质可以预防肿瘤的发展和转移。此外,人体试验尚无确凿证据表明在动物研究中看到的益处也适用于癌症患者。疟疾治疗经验表明,以青蒿素为基础的药物通常耐受性良好。本研究突出了青蒿的传统用途和当代药理学研究,为青蒿在治疗多种疾病中的应用带来了独特见解。