Zhang Miao-Miao, Shi Ai-Hua, Muensterer Oliver J, Uygun Ibrahim, Lyu Yi, Yan Xiao-Peng
Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
Shaanxi Provincial Key Laboratory of Magnetic Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
World J Gastrointest Surg. 2025 Feb 27;17(2):94270. doi: 10.4240/wjgs.v17.i2.94270.
Magnetic compression anastomosis (MCA) offers a simple and reliable technique for inducing anastomoses at any point along the digestive tract. Evidence regarding whether the design of the MCA device influences the anastomosis effect is lacking.
To investigate any difference in the side-to-side colonic anastomosis effect achieved with cylindrical circular ring magnets.
We designed cylindrical and circular ring magnets suitable for side-to-side colonic anastomosis in rats. Thirty Sprague-Dawley rats were randomly divided into a cylindrical group, circular ring group, and cylindrical-circular ring group ( = 10/group). Side-to-side colonic anastomosis was completed by transanal insertion of the magnets without incision of the colon. Operation time, perioperative complications, and magnet discharge time were recorded. Rats were euthanized 4 weeks post-operatively, and anastomotic specimens were obtained. The burst pressure and anastomotic diameter were measured sequentially, and anastomosis formation was observed by naked eye. Histological results were observed by light microscopy.
In all 30 rats, side-to-side colonic anastomosis was completed, for an operation success rate of 100%. No postoperative complications of bleeding and intestinal obstruction occurred, and the postoperative survival rate were 100%. The operation time, magnet discharge time, anastomotic bursting pressure, and anastomotic diameter did not differ significantly among the three designs ( > 0.05). Healing was similar across the groups, with gross specimens showing good anastomotic healing and good mucosal continuity observed on histological analysis.
This study found no significant difference in the establishment of rat side-to-side colonic anastomosis with the use of cylindrical circular ring magnets.
磁压缩吻合术（MCA）为在消化道任何部位进行吻合提供了一种简单可靠的技术。目前缺乏关于MCA装置的设计是否会影响吻合效果的证据。
研究使用圆柱形和环形磁体进行结肠侧侧吻合效果的差异。
我们设计了适用于大鼠结肠侧侧吻合的圆柱形和环形磁体。将30只Sprague-Dawley大鼠随机分为圆柱形组、环形组和圆柱形-环形组（每组n = 10）。通过经肛门插入磁体完成结肠侧侧吻合，无需切开结肠。记录手术时间、围手术期并发症和磁体排出时间。术后4周对大鼠实施安乐死，并获取吻合标本。依次测量破裂压力和吻合口直径，肉眼观察吻合口形成情况。通过光学显微镜观察组织学结果。
30只大鼠均成功完成结肠侧侧吻合，手术成功率为100%。未发生出血和肠梗阻等术后并发症，术后存活率为100%。三种设计的手术时间、磁体排出时间、吻合口破裂压力和吻合口直径差异均无统计学意义（P > 0.05）。各组愈合情况相似，大体标本显示吻合口愈合良好，组织学分析观察到黏膜连续性良好。
本研究发现，使用圆柱形和环形磁体建立大鼠结肠侧侧吻合术无显著差异。
