Sivagurunathan Kajananan, Kaneshamoorthy Prashanthan, Jegathesan Nalayini, Thampipillai Peranantharajah
Internal Medicine, Teaching Hospital Jaffna, Jaffna, LKA.
Cureus. 2025 Feb 4;17(2):e78522. doi: 10.7759/cureus.78522. eCollection 2025 Feb.
Metoclopramide is a widely prescribed antiemetic, particularly in pregnancy, for managing nausea and vomiting. While it is considered safe in most cases, rare extrapyramidal side effects such as acute dystonia with oculogyric crisis can occur. Here, we present a case of a 12-week pregnant woman who developed acute dystonia with oculogyric crisis after treatment with metoclopramide. Oral trihexyphenidyl (Benzhexol) led to rapid symptom resolution. This case emphasizes the need for awareness of rare adverse drug reactions and the importance of early recognition to prevent further complications.
甲氧氯普胺是一种广泛使用的止吐药，尤其在孕期用于控制恶心和呕吐。虽然在大多数情况下它被认为是安全的，但可能会出现罕见的锥体外系副作用，如伴有动眼危象的急性肌张力障碍。在此，我们报告一例12周妊娠妇女在使用甲氧氯普胺治疗后发生伴有动眼危象的急性肌张力障碍的病例。口服苯海索使症状迅速缓解。该病例强调了认识罕见药物不良反应的必要性以及早期识别以预防进一步并发症的重要性。
