Patel Dharmesh J, Chaudhari Kamlesh, Shrivastava Deepti, Dave Apoorva, Shinde Akruti, Gowda Harshith
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Department of Obstretics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2023 Jun 23;15(6):e40842. doi: 10.7759/cureus.40842. eCollection 2023 Jun.
Metoclopramide hydrochloride is a widely used medication for the treatment of gastrointestinal disorders such as nausea, vomiting, and gastroparesis. However, it has been associated with extrapyramidal side effects (EPS) such as tardive dyskinesia, nystagmus, and other locomotive disorders on rare occasions. These reactions are commonly seen in children and females, particularly in young people. In this article, we report a rare case of a 15-week pregnant woman who was prescribed metoclopramide hydrochloride in view of nausea and vomiting, which was later diagnosed as vomiting in pregnancy not relieved with first-line medications, and has later developed drug-induced nystagmus, highlighting its unpredictable nature and shortcomings of management in the pregnant woman. This article will draw the attention of obstetricians and gynecologists to wisely prescribe metoclopramide hydrochloride for treating nausea and vomiting in pregnant women.
盐酸甲氧氯普胺是一种广泛用于治疗胃肠道疾病（如恶心、呕吐和胃轻瘫）的药物。然而，它在极少数情况下会引发锥体外系副作用（EPS），如迟发性运动障碍、眼球震颤和其他运动障碍。这些反应常见于儿童和女性，尤其是年轻人。在本文中，我们报告了一例罕见病例，一名15周妊娠的孕妇因恶心和呕吐被开具了盐酸甲氧氯普胺，后来被诊断为妊娠呕吐，一线药物治疗无效，随后出现了药物性眼球震颤，突出了其不可预测性以及在孕妇管理方面的不足。本文将引起妇产科医生对明智开具盐酸甲氧氯普胺治疗孕妇恶心和呕吐的关注。
