Besong Arrey Emmanuel, Kibu Odette Dzemo, Tanue Elvis Asangbeng, Obinkem Besong Agbor, Kwalar Ginyu Innocentia, Chethkwo Fabrice, Ngum Valentine Ndze, Sandeu Maurice Marcel, Ema Patrick Jolly Ngono, Denis Nkweteyim, Moise Onduo, Gelan Ayana, Kong Jude Dzevela, Nsagha Dickson Shey
Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Global South Artificial Intelligence for Pandemic and Epidemic Preparedness and Response Network (AI4PEP), Toronto, ON, Canada.
Front Public Health. 2025 Feb 24;13:1526454. doi: 10.3389/fpubh.2025.1526454. eCollection 2025.
AIDS is a severe medical condition caused by the human immunodeficiency virus (HIV) that primarily attacks the immune system, specifically CD4+ T lymphocytes (a type of white blood cell crucial for immune response), monocyte macrophages, and dendritic cells. This disease has significant health and socio-economic implications and is one of the primary causes of illness and death globally (UNAIDS, 2022). It presents significant challenges for public health and population well-being, both in developed and developing countries. By conducting a time series analysis, this research seeks to identify any significant changes in HIV rates over the next 4 years in the Kumba District Hospital and provide valuable insights to inform evidence-based decision-making and strategies for preventing and controlling HIV within the Kumba Health District.
A hospital-based retrospective study on HIV/AIDS recorded cases was conducted at the Kumba District Hospital. Using data extraction form, hospital records from 2012 to 2022 were reviewed and data extracted and used to make predictions on the number of future incidence cases. Time series analysis using Auto-Regressive Integrated Moving Average (ARIMA) model was done using Statistical Package for the Social Sciences (SPSS) Version 26.
According to the ARIMA parameter (p,d,q), the results for the Partial Autocorrelation Factor (p) was 1, differencing (d) was 0 and Autocorrelation Factor (q) was 0. Putting these values together, we had the ARIMA model (1,0,0) which predicted an overall increase in HIV incidence cases at the Kumba District Hospital for the upcoming Years (2023-2026).
The ARIMA model was found to be independent of errors and a perfect fit, with a high R-squared value of 0.764 and a -value of 0.410, indicating that the model's predictions aligned well with the observed data. The model predicted an increase in the number of HIV incidence cases over the coming years (2023-2026), potentially suggesting a worsening situation. However, it is important to interpret these predictions with caution and consider other factors that may influence the incidence of HIV in reality.
艾滋病是由人类免疫缺陷病毒(HIV)引起的一种严重疾病,该病毒主要攻击免疫系统,特别是CD4 + T淋巴细胞(一种对免疫反应至关重要的白细胞类型)、单核巨噬细胞和树突状细胞。这种疾病对健康和社会经济有着重大影响,是全球疾病和死亡的主要原因之一(联合国艾滋病规划署,2022年)。它给发达国家和发展中国家的公共卫生和民众福祉都带来了重大挑战。通过进行时间序列分析,本研究旨在确定昆巴地区医院未来4年艾滋病毒感染率的任何显著变化,并提供有价值的见解,为基于证据的决策以及昆巴健康区预防和控制艾滋病毒的策略提供依据。
在昆巴地区医院对艾滋病毒/艾滋病记录病例进行了一项基于医院的回顾性研究。使用数据提取表,查阅了2012年至2022年的医院记录,并提取数据用于预测未来发病病例数。使用社会科学统计软件包(SPSS)第26版,采用自回归积分移动平均(ARIMA)模型进行时间序列分析。
根据ARIMA参数(p,d,q),偏自相关因子(p)的结果为1,差分(d)为0,自相关因子(q)为0。将这些值组合在一起,我们得到了ARIMA模型(1,0,0),该模型预测昆巴地区医院未来几年(2023 - 2026年)艾滋病毒发病病例总体呈上升趋势。
发现ARIMA模型与误差无关且拟合良好,决定系数R平方值较高,为0.764,p值为0.410,表明该模型的预测与观测数据吻合良好。该模型预测未来几年(2023 - 2026年)艾滋病毒发病病例数会增加,这可能意味着情况会恶化。然而,谨慎解读这些预测并考虑其他可能在现实中影响艾滋病毒发病率的因素很重要。