Arbab Safia, Ullah Hanif, Hassan Inam Ul, Wang Weiwei, Qadeer Abdul, Zhang Jiya
Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Key Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Front Vet Sci. 2025 Feb 24;12:1542572. doi: 10.3389/fvets.2025.1542572. eCollection 2025.
Echinococcosis is a parasitic zoonotic disease caused by tapeworm larvae, forming cysts in organs like the liver and lungs. It primarily affects livestock and humans, with significant public health and economic implications worldwide. In the Hazara Division, the prevalence and genetic diversity of the is largely unexplored. Therefore, the current study aims to assess the prevalence o (EG) in livestock.
From April 2023 to April 2024, a total of 480 livestock animals, including buffaloes, cattle, goats, and sheep, were examined for echinococcosis across various slaughterhouses in the Hazara Division. Cysts of were collected from different organs, and the cyst fluid (CF) was microscopically analyzed before DNA extraction. PCR amplification was performed targeting the Cox1 (317 bp) and Cyto B (309 bp) genes to confirm the presence of .
The overall prevalence of Cystic echinococcosis (CE) was 12.2% (59/480), with rates observed in different species as follows: cattle (13.1%), buffaloes (15.2%), goats (6.3%), and sheep (5.7%), (-0.658). District-wise, higher prevalence rates were recorded in Haripur and Mansehra districts (17.5% and 16.2%), followed by Abbottabad and Battagram (12.5% and 11.2%). The lowest prevalence of infection was observed in the upper and lower Kohistan districts, with rates ranging from (8.7% and 7.5%), respectively. The infection was more common in male animals than in females, particularly among those older than 4-5 years ( =0.048). Sex-wise prevalence varied across species, with cattle showing rates of 12.4% in males and 14.3% in females. In buffaloes, prevalence was 20% in males and 13.3% in females, followed by sheep at 5% in males and 6.2% in females, and goats at 8% in males. Most animals in the study were older than three years, with the highest number of cysts found in animals over five years of age. Hydatid cysts were most found in the liver (39.1%) and lungs (34.7%), followed by the kidneys (17.3%) and heart (8.6%), (-0.01).
In conclusion, E.G. is highly prevalent in the livestock population of the Hazara division.
棘球蚴病是一种由绦虫幼虫引起的寄生性人畜共患病，可在肝脏和肺等器官中形成囊肿。它主要影响家畜和人类，在全球范围内具有重大的公共卫生和经济影响。在哈扎拉地区，棘球蚴的流行情况和遗传多样性在很大程度上尚未得到探索。因此，本研究旨在评估家畜中棘球蚴（EG）的流行情况。
2023年4月至2024年4月，在哈扎拉地区的各个屠宰场对包括水牛、牛、山羊和绵羊在内的480头家畜进行了棘球蚴病检查。从不同器官收集棘球蚴囊肿，在提取DNA之前对囊液（CF）进行显微镜分析。针对Cox1（317 bp）和细胞色素B（309 bp）基因进行PCR扩增，以确认棘球蚴的存在。
囊型棘球蚴病（CE）的总体患病率为12.2%（59/480），不同物种的患病率如下：牛（13.1%）、水牛（15.2%）、山羊（6.3%）和绵羊（5.7%），（-0.658）。按地区划分，哈里普尔和曼塞赫拉地区的患病率较高（分别为17.5%和16.2%），其次是阿伯塔巴德和巴塔格拉姆（分别为12.5%和11.2%）。在科希斯坦上区和下区观察到的感染率最低，分别为（8.7%和7.5%）。感染在雄性动物中比在雌性动物中更常见，特别是在4至5岁以上的动物中（=0.048）。不同物种的性别患病率有所不同，牛的雄性患病率为12.4%，雌性患病率为14.3%。在水牛中，雄性患病率为20%，雌性患病率为13.3%，其次是绵羊，雄性患病率为5%，雌性患病率为6.2%，山羊雄性患病率为8%。研究中的大多数动物年龄超过三岁，五岁以上的动物中发现的囊肿数量最多。包虫囊肿最常见于肝脏（39.1%）和肺（34.7%），其次是肾脏（17.3%）和心脏（8.6%），（-0.01）。
总之，EG在哈扎拉地区的家畜群体中高度流行。
