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《欧洲生理学杂志》特刊:生理学与医学领域的人工智能

Special issue European Journal of Physiology: Artificial intelligence in the field of physiology and medicine.

作者信息

Westphal Anika, Mrowka Ralf

机构信息

Thüringer Innovationszentrum Für Medizintechniklösungen (Thimedop), Universitätsklinikum Jena, Jena, Germany.

Experimentelle Nephrologie, KIMIII, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Jena, Germany.

出版信息

Pflugers Arch. 2025 Apr;477(4):509-512. doi: 10.1007/s00424-025-03071-x. Epub 2025 Mar 11.

DOI:10.1007/s00424-025-03071-x
PMID:40067435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11958393/
Abstract

This special issue presents a collection of reviews on the recent advancements and applications of artificial intelligence (AI) in medicine and physiology. The topics covered include digital histopathology, generative AI, explainable AI (XAI), and ethical considerations in AI development and implementation. The reviews highlight the potential of AI to transform medical diagnostics, personalized medicine, and clinical decision making, while also addressing challenges such as data quality, interpretability, and trustworthiness. The contributions demonstrate the growing importance of AI in physiological research and medicine, the need for multi-level ethics approaches in AI development, and the potential benefits of generative AI in medical applications. Overall, this special issue showcases some of the the pioneering aspects of AI in medicine and physiology, covering technical, applicative, and ethical viewpoints, and underlines the remarkable impact of AI on these fields.

摘要

本期特刊呈现了一系列关于人工智能(AI)在医学和生理学领域的最新进展及应用的综述。涵盖的主题包括数字组织病理学、生成式AI、可解释AI(XAI)以及AI开发与实施中的伦理考量。这些综述强调了AI在变革医学诊断、个性化医疗和临床决策方面的潜力,同时也探讨了诸如数据质量、可解释性和可信度等挑战。这些文章展示了AI在生理学研究和医学中日益增长的重要性、AI开发中多层次伦理方法的必要性以及生成式AI在医学应用中的潜在益处。总体而言,本期特刊展示了AI在医学和生理学领域的一些开创性方面,涵盖技术、应用和伦理观点,并突显了AI对这些领域的显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0970/11958393/5379546450ba/424_2025_3071_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0970/11958393/5379546450ba/424_2025_3071_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0970/11958393/5379546450ba/424_2025_3071_Fig1_HTML.jpg

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本文引用的文献

1
Current methods in explainable artificial intelligence and future prospects for integrative physiology.可解释人工智能的当前方法与整合生理学的未来前景。
Pflugers Arch. 2025 Apr;477(4):513-529. doi: 10.1007/s00424-025-03067-7. Epub 2025 Feb 25.
2
Establishing methodological standards for the development of artificial intelligence-based Clinical Decision Support in emergency medicine.建立基于人工智能的急诊医学临床决策支持系统开发的方法学标准。
CJEM. 2025 Feb;27(2):87-95. doi: 10.1007/s43678-024-00826-w. Epub 2025 Feb 7.
3
Causality and scientific explanation of artificial intelligence systems in biomedicine.
生物医学中人工智能系统的因果关系与科学解释。
Pflugers Arch. 2025 Apr;477(4):543-554. doi: 10.1007/s00424-024-03033-9. Epub 2024 Oct 29.
4
Challenges and applications in generative AI for clinical tabular data in physiology.生理学临床表格数据生成式人工智能中的挑战与应用
Pflugers Arch. 2025 Apr;477(4):531-542. doi: 10.1007/s00424-024-03024-w. Epub 2024 Oct 17.
5
Pioneering new paths: the role of generative modelling in neurological disease research.开辟新路径:生成式建模在神经疾病研究中的作用。
Pflugers Arch. 2025 Apr;477(4):571-589. doi: 10.1007/s00424-024-03016-w. Epub 2024 Oct 8.
6
Decoding pathology: the role of computational pathology in research and diagnostics.解读病理学:计算病理学在研究与诊断中的作用。
Pflugers Arch. 2025 Apr;477(4):555-570. doi: 10.1007/s00424-024-03002-2. Epub 2024 Aug 3.
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Explainable artificial intelligence for spectroscopy data: a review.光谱数据的可解释人工智能综述
Pflugers Arch. 2025 Apr;477(4):603-615. doi: 10.1007/s00424-024-02997-y. Epub 2024 Aug 1.
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The ethics of artificial intelligence systems in healthcare and medicine: from a local to a global perspective, and back.医疗保健和医学中人工智能系统的伦理:从地方视角到全球视角,再回归地方视角。
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Nature. 2022 Dec 9. doi: 10.1038/d41586-022-04397-7.