Cho Seung-Hee, Mete Aslı, Cueva Isaiah, Macías-Rioseco Melissa, Fritz Heather, Streitenberger Nicolas, Gonzales-Viera Omar
Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
California Animal Health and Food Safety Laboratory, Davis, branches, University of California-Davis, Davis, CA, USA.
J Vet Diagn Invest. 2025 Jul;37(4):545-551. doi: 10.1177/10406387251324883. Epub 2025 Mar 11.
Abortion in small ruminants poses a significant economic threat and can have zoonotic risk. Although the association between yersiniosis and reproductive complications is known, systematic studies and case series on abortion in sheep and goats are scarce. Here we describe epidemiologic and pathologic findings in 34 cases of - and -associated abortions in sheep and goats, contributing to the understanding of these zoonotic diseases in California. We conducted a 22-y retrospective study to examine microbiologic and pathologic findings in abortion submissions, as well as the geographic and seasonal distribution of the analyzed cases. Yersiniosis-induced abortion was diagnosed in 22 goats and 12 sheep, with all abortions occurring in the last third of gestation. Samples from lung, liver, placenta, and abomasal contents were submitted for aerobic culture; the highest recovery of spp. was from abomasal contents. Microscopically, there was severe necrotizing and suppurative inflammation in the lung, liver, spleen, kidney, and, when present, the placenta, with intralesional bacterial colonies. All cases were received from northern and central California in the winter and spring. Our study provides epidemiologic and pathologic features of spp.-induced abortions in small ruminants and provides critical data to pave the way for future research, surveillance, and preventive strategies.
小型反刍动物流产会造成重大经济威胁，且存在人畜共患病风险。虽然耶尔森菌病与生殖系统并发症之间的关联已为人所知，但关于绵羊和山羊流产的系统性研究及病例系列报道却很匮乏。在此，我们描述了34例绵羊和山羊与[具体疾病]相关流产的流行病学和病理学发现，有助于加深对加利福尼亚州这些人畜共患病的了解。我们开展了一项为期22年的回顾性研究，以检查流产送检样本的微生物学和病理学发现，以及所分析病例的地理和季节分布情况。确诊由耶尔森菌病导致流产的山羊有22只，绵羊有12只，所有流产均发生在妊娠后期。采集了肺、肝、胎盘和皱胃内容物样本进行需氧培养；从皱胃内容物中分离出[具体细菌]的比例最高。显微镜检查显示，肺、肝、脾、肾以及（如有）胎盘出现严重坏死性和化脓性炎症，病灶内有细菌菌落。所有病例均来自加利福尼亚州北部和中部，时间为冬季和春季。我们的研究提供了小型反刍动物由[具体细菌]引起流产的流行病学和病理学特征，并为未来的研究、监测和预防策略提供了关键数据。
