Jeong Jeongyun, Kim Minjoo, Kim Jaehwan, Eom Kidong
Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea (Jeong, J. Kim, Eom); Shine Animal Medical Center, 147 Ogeum-ro, Songpa-gu, Seoul 05550, Republic of Korea (M. Kim).
Can Vet J. 2025 Mar;66(3):255-261.
This report describes the case of a 13-year-old castrated male poodle with respiratory distress and coughing. The dog had had its right thyroid gland and ipsilateral lymph node resected because of thyroid follicular carcinoma originating in the right thyroid gland and metastasis to the ipsilateral medial retropharyngeal lymph node. The dog was initially treated for chronic bronchitis but showed no resolution of the clinical signs. Ultrasonography revealed an enlarged hypoechoic left medial retropharyngeal mass. Computed tomography further revealed an enlarged, heterogeneously enhanced left medial retropharyngeal mass with irregular margins. The mass compressed the laryngeal borders and was considered responsible for the coughing and respiratory distress. Based on the dog's history of thyroid carcinoma, metastatic lymphadenopathy of the left medial retropharyngeal lymph node was suspected, and the mass was surgically removed. Histopathologic examination revealed mild adenomatous salivary hyperplasia with duct ectasia. No evidence of neoplasm or severe inflammation was observed. The final diagnosis was salivary adenomatous hyperplasia in the retropharyngeal region. Salivary adenomatous hyperplasia can be responsible for clinical signs, depending on size and location. Differentiating salivary adenomatous hyperplasia from malignancies based on imaging findings alone can be difficult. This case demonstrated how salivary adenomatous hyperplasia may mimic malignant tumors, particularly in animals with a history of adjacent tumor malignancy. Key clinical message: To the best of our knowledge, this is the first report in a dog of salivary adenomatous hyperplasia that mimicked tumor metastasis. Differentiating between malignant and salivary adenomatous hyperplasia can be difficult using imaging findings alone. Despite being histologically benign, salivary adenomatous hyperplasia may cause clinical signs.
本报告描述了一只13岁去势雄性贵宾犬出现呼吸窘迫和咳嗽的病例。该犬因起源于右侧甲状腺的甲状腺滤泡癌并转移至同侧咽后内侧淋巴结，已接受右侧甲状腺及同侧淋巴结切除术。该犬最初接受慢性支气管炎治疗，但临床症状未缓解。超声检查发现左侧咽后内侧肿块增大且呈低回声。计算机断层扫描进一步显示左侧咽后内侧肿块增大，强化不均匀，边缘不规则。肿块压迫喉边界，被认为是咳嗽和呼吸窘迫的原因。基于该犬的甲状腺癌病史，怀疑左侧咽后内侧淋巴结转移性淋巴结病，遂手术切除肿块。组织病理学检查显示轻度腺瘤样唾液腺增生伴导管扩张。未观察到肿瘤或严重炎症的证据。最终诊断为咽后区唾液腺腺瘤样增生。唾液腺腺瘤样增生可根据其大小和位置导致临床症状。仅根据影像学表现区分唾液腺腺瘤样增生与恶性肿瘤可能困难。本病例展示了唾液腺腺瘤样增生如何可能模仿恶性肿瘤，特别是在有相邻肿瘤恶性病史的动物中。关键临床信息：据我们所知，这是首例犬唾液腺腺瘤样增生模仿肿瘤转移的报告。仅使用影像学表现区分恶性肿瘤和唾液腺腺瘤样增生可能困难。尽管唾液腺腺瘤样增生在组织学上为良性，但可能导致临床症状。
