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经鼻超声乳化抽吸减容治疗2只犬鼻腔肿瘤的有效性

Usefulness of transnasal volume-reduction treatment for nasal tumors by ultrasonic emulsification suction in 2 dogs.

作者信息

Mizutani Shinya, Mizutani Yuko, Goda Yoshimichi, Asanuma Taketoshi, Torisu Shidow

机构信息

Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoinooka, Imabari, Ehime 794-8555, Japan (Mizutani S, Asanuma); University of Miyazaki Veterinary Teaching Hospital, 1-1 Gakuen Kibana-dai Nishi, Miyazaki, Miyazaki 889-2192, Japan (Mizutani Y); Okayama University of Science Veterinary Medical Teaching Hospital, 1-3 Ikoinooka, Imabari, Ehime 794-8555, Japan (Goda); Laboratory of Companion Animal Surgery, Department of Companion Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan (Torisu).

出版信息

Can Vet J. 2025 Mar;66(3):267-272.

PMID:40070945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11891793/
Abstract

Intranasal tumors in dogs are rare neoplastic diseases with obvious clinical signs, such as epistaxis, nasal congestion, and facial deformity. Radiation therapy is the treatment of choice but is not always accessible due to geographical location, logistics, or financial constraints. Other treatments may not be used because of various restrictions. We performed transnasal intranasal tumor volume reduction in 2 dogs with intranasal tumors; 1 dog had an adenocarcinoma and the other had a fibrosarcoma. In both cases, improvement in the quality of life (QOL), including reduced clinical signs and increased activity, was observed ~1 wk after treatment. No obvious complications were associated with this treatment. Although tumor recurrence was noted in both cases, this treatment could be applied multiple times. In conclusion, transnasal nasal tumor volume reduction is a palliative method that contributes to improvement of clinical signs and QOL. Key clinical message: We report palliative treatment of intranasal tumors in dogs. The treatment described in this report is available to most veterinarians and helps improve the QOL of dogs with nasal tumors, including improving respiratory status.

摘要

犬鼻腔肿瘤是罕见的肿瘤性疾病,具有鼻出血、鼻塞和面部畸形等明显临床症状。放射治疗是首选治疗方法,但由于地理位置、后勤保障或经济限制,并非总是可行。由于各种限制,其他治疗方法可能无法使用。我们对2只患有鼻腔肿瘤的犬进行了经鼻鼻腔肿瘤体积缩小术;1只犬患有腺癌,另1只患有纤维肉瘤。在这两个病例中,治疗后约1周观察到生活质量(QOL)有所改善,包括临床症状减轻和活动增加。该治疗未出现明显并发症。虽然两个病例均出现肿瘤复发,但该治疗可多次应用。总之,经鼻鼻腔肿瘤体积缩小术是一种姑息性方法,有助于改善临床症状和生活质量。关键临床信息:我们报告了犬鼻腔肿瘤的姑息性治疗。本报告中描述的治疗方法大多数兽医都可采用,有助于改善患有鼻腔肿瘤犬的生活质量,包括改善呼吸状况。

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Usefulness of transnasal volume-reduction treatment for nasal tumors by ultrasonic emulsification suction in 2 dogs.经鼻超声乳化抽吸减容治疗2只犬鼻腔肿瘤的有效性
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本文引用的文献

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A prospective, multi-centre, Veterinary Radiation Therapy Oncology Group study reveals potential efficacy of toceranib phosphate (Palladia) as a primary or adjuvant agent in the treatment of canine nasal carcinoma.一项前瞻性、多中心的兽医放射治疗肿瘤学组研究显示,磷酸托西拉尼(Palladia)作为治疗犬鼻癌的一线或辅助药物具有潜在疗效。
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