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计算机辅助测量人类精液中精子游动速度:结果与体外受精试验的相关性

Computer-assisted measurement of sperm swimming speed in human semen: correlation of results with in vitro fertilization assays.

作者信息

Holt W V, Moore H D, Hillier S G

出版信息

Fertil Steril. 1985 Jul;44(1):112-9. doi: 10.1016/s0015-0282(16)48687-5.

Abstract

A semiautomatic computerized technique for the measurement of sperm swimming speed is presented. The equipment is easy to use and would be suitable for routine clinical laboratories. The value of the sperm speed measurements obtained from over 100 individuals in relation to fertility has been studied by the correlation of these results with human in vitro fertilization (IVF) data and sperm penetrating capability in the zona-free hamster egg assay. The results show that sperm speed measurements correlate very well with those of the IVF, both human and hamster, and can be used successfully, in conjunction with multivariate statistical methods, to predict the outcomes of such techniques with about 75% accuracy.

摘要

本文介绍了一种用于测量精子游动速度的半自动计算机技术。该设备易于使用,适用于常规临床实验室。通过将这些结果与人类体外受精(IVF)数据以及无透明带仓鼠卵试验中的精子穿透能力进行相关性分析,研究了从100多名个体获得的精子速度测量值与生育能力的关系。结果表明,精子速度测量值与人类和仓鼠的IVF结果相关性非常好,并且可以与多元统计方法结合成功使用,以约75%的准确率预测此类技术的结果。

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