Gerardos Angelica Maria, Forys Aleksander, Trzebicka Barbara, Pispas Stergios
Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece.
Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece.
Polymers (Basel). 2025 Mar 6;17(5):701. doi: 10.3390/polym17050701.
Stimuli-responsive polymeric nanostructures are compelling vectors for a wide range of application opportunities. The objective we sought was to broaden the array of self-assembling amphiphilic copolymers with stimuli-responsive characteristics by introducing a hydrophilic tunable monomer, (2-dimethylamino)ethyl methacrylate (DMAEMA), together with a hydrophilic one, lauryl methacrylate (LMA), within linear and branched copolymer topologies. Size exclusion chromatography was used to evaluate the resultant linear and hyperbranched copolymers' molecular weight and dispersity, and FT-IR and H-NMR spectroscopy techniques were used to delineate their chemical structure. The structural changes in the obtained self-organized supramolecular structures were thoroughly investigated using aqueous media with varying pH and salinity by dynamic light scattering (DLS), fluorescence spectroscopy (FS), and transmission electron microscopy (TEM). The nanoscale assemblies formed by the amphiphiles indicate significant potential for applications within the field of nanotechnology.
刺激响应性聚合物纳米结构是适用于广泛应用机会的引人注目的载体。我们追求的目标是，通过在线性和支化共聚物拓扑结构中引入亲水性可调单体甲基丙烯酸(2-二甲基氨基)乙酯(DMAEMA)以及亲水性单体甲基丙烯酸月桂酯(LMA)，来拓宽具有刺激响应特性的自组装两亲共聚物的种类。使用尺寸排阻色谱法评估所得线性和超支化共聚物的分子量和分散度，并使用傅里叶变换红外光谱(FT-IR)和核磁共振氢谱(H-NMR)技术来描绘它们的化学结构。通过动态光散射(DLS)、荧光光谱(FS)和透射电子显微镜(TEM)，使用具有不同pH值和盐度的水性介质，对获得的自组装超分子结构的结构变化进行了深入研究。两亲物形成的纳米级组装体在纳米技术领域显示出巨大的应用潜力。
