和的植物化学见解与治疗潜力。

Phytochemical Insights and Therapeutic Potential of and .

作者信息

Kozhantayeva Akmaral, Iskakova Zhanar, Ibrayeva Manshuk, Sapiyeva Ardak, Arkharbekova Moldir, Tashenov Yerbolat

机构信息

Research Institute of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, Kazakhstan.

Department of Chemistry, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, Kazakhstan.

出版信息

Molecules. 2025 Mar 6;30(5):1186. doi: 10.3390/molecules30051186.

DOI:10.3390/molecules30051186

PMID:40076409

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11901623/

Abstract

The genus, particularly and , is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides a comprehensive analysis of their phytochemical constituents, with an emphasis on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally, this review evaluates the biological activities of species in relation to their chemical composition, while also considering the limitations of current studies, such as the lack of in vivo or clinical trials. The literature for this review was sourced from scientific databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to 2024. Future studies should focus on optimizing extraction methods, elucidating synergistic bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety.

摘要

该属，特别是[具体物种1]和[具体物种2]，因其丰富的植物化学成分和广泛的药用特性而闻名。这些物种富含多酚、黄酮类化合物和单宁，这些成分赋予了它们强大的抗氧化、抗菌和抗癌活性。本综述对其植物化学成分进行了全面分析，重点关注包括发酵在内的加工方法如何影响生物活性。值得注意的是，发酵提高了关键生物活性化合物的水平，如oenothein B、没食子酸和鞣花酸，从而增加了它们的药理潜力。此外，本综述评估了[物种名称]物种与其化学成分相关的生物活性，同时也考虑了当前研究的局限性，如缺乏体内或临床试验。本综述的文献来自科学数据库，包括PubMed、Scopus和ScienceDirect，涵盖了2010年至2024年的研究。未来的研究应专注于优化提取方法、阐明协同生物活性，并进行深入的临床试验以验证其有效性和安全性。