• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

L.乙醇提取物和乙酸乙酯提取物的植物化学分析、抗氧化及抗菌潜力

Phytochemical Profiling, Antioxidant and Antimicrobial Potentials of Ethanol and Ethyl Acetate Extracts of L.

作者信息

Kozhantayeva Akmaral, Tursynova Nurgul, Kolpek Ainagul, Aibuldinov Yelaman, Tursynova Arailym, Mashan Togzhan, Mukazhanova Zhazira, Ibrayeva Manshuk, Zeinuldina Aizhan, Nurlybayeva Aisha, Iskakova Zhanar, Tashenov Yerbolat

机构信息

Research Institute of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, Kazakhstan.

Department of Chemistry, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, Kazakhstan.

出版信息

Pharmaceuticals (Basel). 2024 Jul 27;17(8):996. doi: 10.3390/ph17080996.

DOI:10.3390/ph17080996
PMID:39204101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357188/
Abstract

The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.48 ± 3.44 mg GAE/g DE) and flavonoid content (24.18 ± 1.06 mg QE/g DE) compared to ChL-EtOAc. HPLC-UV-ESI/MS identified key phenolic acids and flavonoids, including gallic acid, chlorogenic acid, and quercetin 3-glucoside. FT-IR analysis confirmed the presence of characteristic functional groups. Antioxidant assays revealed strong DPPH scavenging and FRAP activities, with ChL-EtOH showing superior results (IC = 21.31 ± 0.65 μg/mL and 18.13 ± 0.15 μg/mL, respectively). Additionally, ChL-EtOH displayed notable antimicrobial efficacy against Gram-positive and Gram-negative bacteria, as well as the fungal strain . These findings suggest that ethanol extraction is more efficient for isolating bioactive compounds from ChL, underscoring its potential for pharmaceutical and nutraceutical applications.

摘要

该研究调查了从哈萨克斯坦采集的光果甘草（ChL）的乙醇提取物（ChL-EtOH）和乙酸乙酯提取物（ChL-EtOAc）的植物化学特征、抗氧化能力和抗菌活性。与ChL-EtOAc相比，ChL-EtOH提取物表现出更高的总酚含量（267.48±3.44 mg GAE/g DE）和黄酮含量（24.18±1.06 mg QE/g DE）。HPLC-UV-ESI/MS鉴定出了关键的酚酸和黄酮类化合物，包括没食子酸、绿原酸和槲皮素3-葡萄糖苷。傅里叶变换红外光谱（FT-IR）分析证实了特征官能团的存在。抗氧化试验显示出较强的二苯基苦味酰基自由基（DPPH）清除能力和铁离子还原抗氧化能力（FRAP），ChL-EtOH的结果更优（IC分别为21.31±0.65 μg/mL和18.13±0.15 μg/mL）。此外，ChL-EtOH对革兰氏阳性菌、革兰氏阴性菌以及真菌菌株均表现出显著的抗菌效果。这些发现表明，乙醇提取法从光果甘草中分离生物活性化合物的效率更高，突出了其在制药和营养保健品应用方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/765a6f11c77e/pharmaceuticals-17-00996-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/0b6a4598652e/pharmaceuticals-17-00996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/74284ae4e17b/pharmaceuticals-17-00996-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/7003eeedd996/pharmaceuticals-17-00996-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/e00147a530ce/pharmaceuticals-17-00996-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/765a6f11c77e/pharmaceuticals-17-00996-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/0b6a4598652e/pharmaceuticals-17-00996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/74284ae4e17b/pharmaceuticals-17-00996-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/7003eeedd996/pharmaceuticals-17-00996-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/e00147a530ce/pharmaceuticals-17-00996-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f93/11357188/765a6f11c77e/pharmaceuticals-17-00996-g005.jpg

相似文献

1
Phytochemical Profiling, Antioxidant and Antimicrobial Potentials of Ethanol and Ethyl Acetate Extracts of L.L.乙醇提取物和乙酸乙酯提取物的植物化学分析、抗氧化及抗菌潜力
Pharmaceuticals (Basel). 2024 Jul 27;17(8):996. doi: 10.3390/ph17080996.
2
Phytochemicals, Antioxidant and Antimicrobial Potentials and LC-MS Analysis of Desf. Extracts.植物化学物质、抗氧化和抗菌潜力及 Desf. 提取物的 LC-MS 分析。
Molecules. 2023 Feb 28;28(5):2263. doi: 10.3390/molecules28052263.
3
Phytochemical Composition, Antioxidant, and Antimicrobial Attributes of Different Solvent Extracts from Buch.-Ham. ex. D. Don Leaves.不同溶剂萃取的 Buch.-Ham. ex. D. Don 叶的植物化学成分、抗氧化和抗菌特性。
Biomolecules. 2019 Aug 9;9(8):357. doi: 10.3390/biom9080357.
4
Phytochemical Analysis of L. Aerial Flowering Parts Serial Solvent Extracts and Its Antibacterial and Antioxidant Activities.L.地上开花部分系列溶剂提取物的植物化学分析及其抗菌和抗氧化活性。
Life (Basel). 2024 Jul 19;14(7):900. doi: 10.3390/life14070900.
5
Phytochemical Composition, Antioxidant, Antibacterial, and Enzyme Inhibitory Activities of Various Organic Extracts from (Hook.f.) Woodson.（胡克.f.）伍德森不同有机提取物的植物化学成分、抗氧化、抗菌及酶抑制活性
Plants (Basel). 2022 Jul 28;11(15):1964. doi: 10.3390/plants11151964.
6
Phytochemical screening, HPLC analysis, antimicrobial and antioxidant effect of Euphorbia parviflora L. (Euphorbiaceae Juss.).植物化学成分筛查、高效液相色谱分析、Euphorbia parviflora L.（大戟科 Juss.）的抗菌和抗氧化作用。
Sci Rep. 2024 Mar 7;14(1):5627. doi: 10.1038/s41598-024-55905-w.
7
Phytochemical Investigation and in vitro Antimicrobial and Antioxidant Activities Evaluation of Wiens and Polhill.维恩斯和波尔希尔的植物化学研究及其体外抗菌和抗氧化活性评估
J Exp Pharmacol. 2024 Feb 13;16:71-80. doi: 10.2147/JEP.S452098. eCollection 2024.
8
Phytochemical Composition, Antioxidant Activity, and Enzyme Inhibitory Activities (α-Glucosidase, Xanthine Oxidase, and Acetylcholinesterase) of .[植物名称]的化学成分、抗氧化活性以及对α-葡萄糖苷酶、黄嘌呤氧化酶和乙酰胆碱酯酶的抑制活性。
Molecules. 2021 Jul 24;26(15):4472. doi: 10.3390/molecules26154472.
9
Comparative HPLC-DAD-ESI-QTOF/MS/MS Analysis of Bioactive Phenolic Compounds Content in the Methanolic Extracts from Flowering Herbs of Species and Their Free Radical Scavenging and Antimicrobial Activities.物种开花草本植物甲醇提取物中生物活性酚类化合物含量的比较HPLC-DAD-ESI-QTOF/MS/MS分析及其自由基清除和抗菌活性
Pharmaceutics. 2023 Mar 16;15(3):964. doi: 10.3390/pharmaceutics15030964.
10
Variation in secondary metabolite production as well as antioxidant and antibacterial activities of Zingiber zerumbet (L.) at different stages of growth.不同生长阶段的红球姜（Zingiber zerumbet (L.)）次生代谢产物产量以及抗氧化和抗菌活性的变化。
BMC Complement Altern Med. 2016 Mar 22;16:104. doi: 10.1186/s12906-016-1072-6.

引用本文的文献

1
Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Extracts from High-Altitude Regions of Nepal.尼泊尔高海拔地区野生提取物的生物活性成分、抗氧化活性及抗癌潜力评估
Curr Issues Mol Biol. 2025 Aug 5;47(8):624. doi: 10.3390/cimb47080624.
2
Green Synthesis of Silver Nanoparticles Using Ethanolic Extract: Phytochemical Profiling, Characterization, and Antimicrobial Evaluation.使用乙醇提取物绿色合成银纳米颗粒：植物化学分析、表征及抗菌评估
Int J Mol Sci. 2025 Jun 8;26(12):5505. doi: 10.3390/ijms26125505.
3
Phytochemical Insights and Therapeutic Potential of and .

本文引用的文献

1
Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases.氧化应激：抗氧化植物化学物质在疾病预防和治疗中的作用。
Int J Mol Sci. 2024 Mar 13;25(6):3264. doi: 10.3390/ijms25063264.
2
Flavonoids: A treasure house of prospective pharmacological potentials.黄酮类化合物：一个具有潜在药理潜力的宝库。
Heliyon. 2024 Mar 9;10(6):e27533. doi: 10.1016/j.heliyon.2024.e27533. eCollection 2024 Mar 30.
3
Preparation, Characterization, and Antioxidant Activities of Extracts from L. Flowers.金莲花属花卉提取物的制备、表征及抗氧化活性
和的植物化学见解与治疗潜力。
Molecules. 2025 Mar 6;30(5):1186. doi: 10.3390/molecules30051186.
Molecules. 2024 Jan 29;29(3):633. doi: 10.3390/molecules29030633.
4
Phytochemical and Nutraceutical Screening of Ethanol and Ethyl Acetate Phases of Romanian Herba ().罗马尼亚草（）的乙醇和乙酸乙酯相的植物化学和营养筛选
Molecules. 2023 Nov 27;28(23):7804. doi: 10.3390/molecules28237804.
5
Antifungal activity and mechanism of action of natural product derivates as potential environmental disinfectants.天然产物衍生物作为潜在环境消毒剂的抗真菌活性和作用机制。
J Ind Microbiol Biotechnol. 2023 Feb 17;50(1). doi: 10.1093/jimb/kuad036.
6
Efficacy of various extracting solvents on phytochemical composition, and biological properties of Mentha longifolia L. leaf extracts.不同提取溶剂对长叶薄荷叶片提取物的植物化学成分、生物活性的影响。
Sci Rep. 2023 Oct 21;13(1):18028. doi: 10.1038/s41598-023-45030-5.
7
Back to Nature: Medicinal Plants as Promising Sources for Antibacterial Drugs in the Post-Antibiotic Era.回归自然：药用植物作为抗生素后时代抗菌药物的潜在来源
Plants (Basel). 2023 Aug 28;12(17):3077. doi: 10.3390/plants12173077.
8
Studies of the Variability of Biologically Active Compounds and Antioxidant Activity in Organically, Biodynamically, and Naturally Grown and Fermented Fireweed ( (L.) Holub) Leaves.有机、生物动力和自然生长及发酵的柳兰（(L.) Holub）叶中生物活性化合物的变异性及抗氧化活性研究。
Plants (Basel). 2023 Jun 16;12(12):2345. doi: 10.3390/plants12122345.
9
Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis.季节、贮藏和提取方法对榄仁树植物化学成分的影响。
BMC Plant Biol. 2023 Mar 25;23(1):162. doi: 10.1186/s12870-023-04144-8.
10
Therapeutic Potential of Phenolic Compounds in Medicinal Plants-Natural Health Products for Human Health.药用植物中酚类化合物的治疗潜力——天然保健品对人类健康的作用。
Molecules. 2023 Feb 15;28(4):1845. doi: 10.3390/molecules28041845.