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.的抗炎机制研究进展

Research Progress on Anti-Inflammatory Mechanism of .

作者信息

Wu Ningning, Wang Siqi, Zhang Yuqian, Wang Siming

机构信息

School of Basic Medical Sciences, Hebei University, Baoding 071000, China.

出版信息

Int J Mol Sci. 2025 Feb 23;26(5):1911. doi: 10.3390/ijms26051911.

Abstract

The incidence of various inflammatory diseases has remained high. is a kind of Chinese herbal medicine with a wide range of pharmacological uses and application value. It has anti-inflammatory, antibacterial, antioxidant, hepatoprotective and other pharmacological activities. The monomeric compounds that have been confirmed to have anti-inflammatory effects are luteolin, chrysoerilol, artemetin, chlorogenic acid, neochlorogenic acid, cryptchlorogenic acid, isochlorogenic acid A, isochlorogenic acid B, isochlorogenic acid C and 1,3--dicaffeoylquinic acid. This article introduces the relationship between and inflammation, the anti-inflammatory components of , the modulation of each component on the inflammatory transduction signal pathway, and the TLR2/MyD88/NF-KB anti-inflammatory signaling pathway, providing a theoretical basis for anti-inflammatory research on and clinical medication using .

摘要

各种炎症性疾病的发病率一直居高不下。是一种具有广泛药理用途和应用价值的中药材。它具有抗炎、抗菌、抗氧化、保肝等药理活性。已证实具有抗炎作用的单体化合物有木犀草素、 Chrysoerilol、青蒿素、绿原酸、新绿原酸、隐绿原酸、异绿原酸A、异绿原酸B、异绿原酸C和1,3 - 二咖啡酰奎尼酸。本文介绍了与炎症的关系、的抗炎成分、各成分对炎症转导信号通路的调节以及TLR2/MyD88/NF - KB抗炎信号通路,为对进行抗炎研究及临床用药提供理论依据。

需注意,原文中“ is a kind of Chinese herbal medicine...”这里的“”指代不明,翻译时保留了原文的指代问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/11900443/e09ef08f0ee6/ijms-26-01911-g001.jpg

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