Dunn Andrew S, Fastman Barbara Rabin, Weinberg Alan, Condrat Lindsay, Fraser Allison, Khan Rabia, Zambrano Loor Marjorie P, Rajda Geetanjali, Perez Octavio L, Adawi Ayham, Kam Korey, Parekh Ankit, Varga Andrew W, Vincent Richard L
Division of Hospital Medicine, Department of Medicine at Mount Sinai Hospital, New York, New York, USA.
Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
J Sleep Res. 2025 Mar 13:e70041. doi: 10.1111/jsr.70041.
Poor sleep is common in hospitalised patients due to multiple factors, including disruption of the circadian rhythm. Few studies have examined programmable artificial lighting systems in hospital patient rooms, and few have achieved meaningful improvement in sleep. We sought to determine how novel dynamic lighting affects sleep timing and duration compared to standard hospital lighting. Patients were admitted to rooms on a cardiology unit with customised intervention or standard lighting. The lighting system delivered blue-enriched light during the day, a melanopic stimulus twice daily and blue-depleted light in the evening. Sleep/wake probability was measured in 30-s epochs using mattress sensors to capture sleep timing and nocturnal sleep duration. Subjective sleep duration and alertness were assessed with sleep diaries and the Karolinska Sleepiness Scale (KSS), respectively. A total of 87 patients were enrolled. Subjects experiencing customised lighting demonstrated significantly advanced rest/wake activity phase by 160 min and overall greater sleep probability. Overnight sleep duration (11 p.m.-7 a.m.) was 66 min greater in the lighting condition (266 vs. 200 min, p < 0.05). Patients in the intervention group reported higher levels of alertness during the morning (KSS score 3.8 vs. 4.9, p = 0.01) and evening (5.4 vs. 7.1, p = 0.01). A lighting system programmed to entrain the circadian rhythm and provide a daytime melanopic stimulus on a hospital unit was associated with advanced circadian phase, increased nocturnal sleep duration and increased perceived morning and evening alertness. These results suggest that dynamic lighting systems have the potential to improve sleep for hospitalised patients.
由于多种因素，包括昼夜节律紊乱，睡眠不佳在住院患者中很常见。很少有研究考察医院病房中的可编程人工照明系统，也很少有研究在改善睡眠方面取得显著成效。我们试图确定与标准医院照明相比，新型动态照明如何影响睡眠时间和时长。患者被收治到心脏病科病房，病房配备定制化干预照明或标准照明。该照明系统在白天提供富含蓝光的光线，每天两次提供黑素视蛋白刺激，并在晚上提供蓝光减少的光线。使用床垫传感器以30秒的时间段测量睡眠/觉醒概率，以捕捉睡眠时间和夜间睡眠时间。分别通过睡眠日记和卡罗林斯卡嗜睡量表（KSS）评估主观睡眠时间和警觉性。总共招募了87名患者。接受定制照明的受试者的休息/觉醒活动阶段显著提前了160分钟，总体睡眠概率更高。在照明条件下，夜间睡眠时间（晚上11点至早上7点）长66分钟（266分钟对200分钟，p<0.05）。干预组患者在早晨（KSS评分3.8对4.9，p=0.01）和晚上（5.4对7.1，p=0.01）报告的警觉性更高。一种经过编程以调节昼夜节律并在医院病房提供白天黑素视蛋白刺激的照明系统与昼夜节律提前、夜间睡眠时间增加以及早晨和晚上的警觉性提高有关。这些结果表明，动态照明系统有可能改善住院患者的睡眠。
