Trześniewska-Ofiara Zuzanna, Mendrycka Mariola, Woźniak-Kosek Agnieszka
Department of Laboratory Diagnostics, Mazovian Specialist Hospital Ltd., Radom, Poland.
Department of Cosmetology, Faculty of Medical Sciences and Health Sciences, Casimir Pulaski University of Radom, Radom, Poland.
Acta Biochim Pol. 2025 Feb 27;72:14082. doi: 10.3389/abp.2025.14082. eCollection 2025.
Urinary tract infections (UTI) are a significant problem among populations worldwide. It is mainly associated with the increasing incidence of recurrence, complications and the increasing drug resistance of uropathogens. The aim of this study was to demonstrate the prevalence of resistance among pathogens causing urinary tract infections. The material for the study was data obtained from the Mazovian Specialized Hospital (M.S.H) in Radom over a period of 2 years. Urine was collected from hospitalized patients with UTI. Statistical calculations were performed using statistical software. During the study period, 3,917 patients underwent microbiological examination of urine, and almost 15% of them were found to be infected with UTI. Based on statistical analysis of drug susceptibility of the most common uropathogens, it was shown that urinary tract infections caused by or , among others, often show high resistance to fluoroquinolones and β-lactam antibiotics. strains have been shown to be more resistant to aminoglycosides and fluoroquinolones than to beta-lactams. In the case of aeruginisa, resistance to fluoroquinolones predominates. On the other hand, UTI caused by Acientobacter baumannii should be treated based on the results of drug susceptibility testing due to the increasing prevalence of multidrug-resistant strains.
尿路感染(UTI)是全球人群中的一个重要问题。它主要与复发率、并发症发生率的增加以及尿路病原体耐药性的上升有关。本研究的目的是证明引起尿路感染的病原体的耐药率。研究材料是从拉多姆的马佐夫舍专科医院(M.S.H)在两年时间内获得的数据。从患有UTI的住院患者中收集尿液。使用统计软件进行统计计算。在研究期间,3917名患者接受了尿液微生物学检查,其中近15%被发现感染了UTI。基于对最常见尿路病原体药敏性的统计分析,结果表明,由 或 等引起的尿路感染通常对氟喹诺酮类和β-内酰胺类抗生素表现出高度耐药性。 菌株已显示出对氨基糖苷类和氟喹诺酮类的耐药性高于对β-内酰胺类的耐药性。在铜绿假单胞菌的情况下,对氟喹诺酮类的耐药性占主导。另一方面,由于多重耐药菌株的患病率不断上升,由鲍曼不动杆菌引起的UTI应根据药敏试验结果进行治疗。