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利用微生物生物电化学系统进行生化生产。

Biochemical production with microbial bioelectrochemical systems.

作者信息

Boto Santiago T, Cristiani Lorenzo, Rosenbaum Miriam A

机构信息

Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), 07745 Jena, Germany.

Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), 07745 Jena, Germany; Faculty of Biological Sciences, Friedrich-Schiller-University Jena, 07745 Jena, Germany.

出版信息

Curr Opin Biotechnol. 2025 Jun;93:103291. doi: 10.1016/j.copbio.2025.103291. Epub 2025 Mar 13.

Abstract

Microbial bioelectrochemical systems (BES) represent a promising platform for sustainable biochemical production by leveraging microbial electrocatalysis. These systems utilize electrical energy to drive microbial metabolic processes, enabling the recovery of CO₂ into valuable organic molecules such as methane, acetate, ethanol, and other biochemicals. This approach aligns with global efforts to mitigate greenhouse gas emissions and create circular carbon economies. The advancement of BES technology requires both scale-down and scale-up strategies to ensure feasibility and scalability. Scale-down approaches focus on optimizing operational parameters, enhancing electron transfer efficiencies, and understanding microbial community dynamics under controlled conditions. Scale-up efforts address the challenges of maintaining system stability, energy efficiency, and economic viability in larger, industrial-scale operations. Together, these strategies bridge the gap between fundamental laboratory research and real-world applications, positioning microbial BES as a key technology for sustainable biochemical production and captured carbon utilization.

摘要

微生物生物电化学系统(BES)通过利用微生物电催化作用,为可持续生化生产提供了一个有前景的平台。这些系统利用电能驱动微生物代谢过程,能够将二氧化碳转化为有价值的有机分子,如甲烷、乙酸盐、乙醇和其他生化物质。这种方法与全球减缓温室气体排放和创建循环碳经济的努力相一致。BES技术的进步需要缩小规模和扩大规模的策略,以确保可行性和可扩展性。缩小规模的方法侧重于优化操作参数、提高电子转移效率以及了解受控条件下的微生物群落动态。扩大规模的努力则解决了在更大规模的工业操作中维持系统稳定性、能源效率和经济可行性的挑战。这些策略共同弥合了基础实验室研究与实际应用之间的差距,使微生物BES成为可持续生化生产和碳捕获利用的关键技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b36/12154207/783482c75ba9/gr1.jpg

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