Dereddy Narendra, Ruth Deborah, Zhu Jianbin, Pepe Julie, Oh William
Center for Neonatal Care, Advent Health for Children, Orlando, FL, 32804, USA.
University of Central Florida College of Medicine, Orlando, FL, USA.
J Perinatol. 2025 Mar 16. doi: 10.1038/s41372-025-02261-w.
To determine the insensible water losses (IWL) in preterm infants cared for in incubators with 70% or 90% relative humidity (RH).
This was a single center retrospective study of extremely preterm infants between 22- and 28-weeks gestational ages nursed in 70% and 90% RH. IWL was calculated using a formula that utilized infants' fluid intake, urine output and body weight changes. IWL between the two groups were compared using independent t-test. Multivariate linear regression was used to assess the effects of humidity on IWL after adjusting for confounding variables.
IWL was higher in infants nursed in 70% RH when compared with those nursed in 90% RH (47.7 ± 30.3 vs. 28.8 ± 39.6, p = 002). Multivariate linear regression analysis showed that RH has an independent effect on the insensible water loss.
Extremely preterm infants nursed in incubator with 70% RH have higher IWL than infants nursed in 90% RH.
确定在相对湿度(RH)为70%或90%的培养箱中护理的早产儿的不显性失水量(IWL)。
这是一项单中心回顾性研究,对胎龄在22至28周的极早产儿在70%和90%的相对湿度下进行护理。IWL采用一个利用婴儿液体摄入量、尿量和体重变化的公式进行计算。两组之间的IWL使用独立t检验进行比较。在调整混杂变量后,采用多元线性回归评估湿度对IWL的影响。
与在90%相对湿度下护理的婴儿相比,在70%相对湿度下护理的婴儿IWL更高(47.7±30.3对28.8±39.6,p = 0.02)。多元线性回归分析表明,相对湿度对不显性失水量有独立影响。
在相对湿度为70%的培养箱中护理的极早产儿比在90%相对湿度下护理的婴儿有更高的IWL。