Yi Jiao, Chen Lei, Meng Xianglian, Chen Yi
Department of Obstetrics and Gynecology, Maternal and Child Medicine Center affiliated with, Hefei Maternal and Child Health Care Hospital, Anhui Medical University, Hefei, China.
BMC Pregnancy Childbirth. 2025 Mar 15;25(1):287. doi: 10.1186/s12884-025-07388-4.
To identify the effectiveness and safety induction using a double-balloon catheter in the setting of Coronavirus disease 2019 (COVID-19) infection.
This retrospective study included 577 COVID-19-afected women who underwent induction of labor with a double balloon catheter or spontaneously started delivery between December 7, 2022, and June 20, 2023; 154 women underwent induction of labor (double balloon catheter, study group) and 423 women underwent spontaneous started delivery (control group). Maternal and neonatal outcomes and complications during labor were assessed and compared.
Duration of the first stage of labor and total labor in the study group were significantly shorter than those in the control group (P < 0.05). There were no statistically significant differences between the two groups in terms of maternal delivery complications (P > 0.05). The two groups did differ significantly in the occurrences of pregnancy induced hypertension and gestational diabetes mellitus (P < 0.05). The neonatal prognosis was similar between the two groups (P > 0.05). After adjusting for maternal age, body mass index, gestational age at delivery, gestational age at infection, gravidity, parity, oxytocin administration and failure of progress of labor, multivariate logistic regression analysis found that COVID-19-afected women who received the double balloon catheter were not associated with an increased risk of fetal distress, intrapartum fever and cesarean section (P > 0.05).
Double balloon catheter is an effective and safe method for labor induction in pregnant women with COVID-19 and is not associated with an increased risk of fetal distress, intrapartum fever and cesarean section.
确定在2019年冠状病毒病（COVID-19）感染情况下使用双球囊导管引产的有效性和安全性。
这项回顾性研究纳入了577名在2022年12月7日至2023年6月20日期间接受双球囊导管引产或自然发动分娩的COVID-19感染女性；154名女性接受了引产（双球囊导管，研究组），423名女性自然发动分娩（对照组）。评估并比较了分娩期间的母婴结局及并发症。
研究组第一产程和总产程的持续时间显著短于对照组（P < 0.05）。两组在产妇分娩并发症方面无统计学显著差异（P > 0.05）。两组在妊娠期高血压和妊娠期糖尿病的发生率上有显著差异（P < 0.05）。两组新生儿预后相似（P > 0.05）。在调整产妇年龄、体重指数、分娩时孕周、感染时孕周、孕次、产次、缩宫素使用及产程进展失败等因素后，多因素逻辑回归分析发现，接受双球囊导管的COVID-19感染女性发生胎儿窘迫、产时发热和剖宫产的风险并未增加（P > 0.05）。
双球囊导管是COVID-19感染孕妇引产的一种有效且安全的方法，与胎儿窘迫、产时发热和剖宫产风险增加无关。
