Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, No. 745, Wuluo Road, Hongshan District, Wuhan, 430070, China.
Department of Gynaecology and Obstetrics, Wuhan University of Science and Technology, No.2, Huangjiahu West Road, Hongshan District, Wuhan, 430065, China.
BMC Pregnancy Childbirth. 2021 Jan 6;21(1):17. doi: 10.1186/s12884-020-03513-7.
This study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using a double-balloon catheter (DBC) within 12 h versus within 12-24 h.
In this retrospective study, a total of 58 pregnant women at 14 + 0 weeks to 27 + 6 weeks of gestation were enrolled as research subjects, and they underwent the intended termination of pregnancy at our birth centre from January 1, 2017, to June 31, 2019. Based on the duration of DBC, the patients were divided into two groups, namely, the DBC group within 12 h and the DBC group within 12-24 h.
All 58 cases were successful vaginal deliveries, and no one chose to undergo caesarean section. The success rate of induction (successful abortion of the foetus and placenta without the implementation of dilation and evacuation) was higher in the DBC group within 12-24 h (96.3%, 29/31) than in the DBC group within 12 h (71.0%, 18/27) (p < 0.05). Additionally, the time from DBC removal to delivery in the DBC group within 12-24 h was significantly shorter than that in the DBC group within 12 h (3.0 h versus 17.8 h) (p < 0.05), and the degree of cervical dilation after DBC removal in the DBC group within 12-24 h was larger than that in the DBC group within 12 h (p < 0.05).
In the clinic, the placement time of DBC generally lasts for approximately 12 h. However, considering that the cervical condition is immature in the mid-trimester, properly extending the placement time of DBC to 24 h will benefit cervical ripening and reduce the chance of dilation and evacuation.
本研究旨在评估在妊娠中期使用双球囊导管（DBC）在 12 小时内引产与在 12-24 小时内引产的疗效和安全性。
在这项回顾性研究中，共有 58 名孕妇在 14+0 周至 27+6 周的妊娠期间被纳入研究对象，他们在我们的分娩中心从 2017 年 1 月 1 日至 2019 年 6 月 31 日期间进行了计划终止妊娠。根据 DBC 的持续时间，患者被分为两组，即 DBC 组在 12 小时内和 DBC 组在 12-24 小时内。
所有 58 例均成功阴道分娩，无一例选择剖宫产。DBC 组在 12-24 小时内（96.3%，29/31）的引产成功率（胎儿和胎盘成功流产而无需扩张和排空）高于 DBC 组在 12 小时内（71.0%，18/27）（p<0.05）。此外，DBC 组在 12-24 小时内的 DBC 取出至分娩时间明显短于 DBC 组在 12 小时内（3.0 小时与 17.8 小时）（p<0.05），DBC 组在 12-24 小时内的 DBC 取出后宫颈扩张程度大于 DBC 组在 12 小时内（p<0.05）。
在临床上，DBC 的放置时间通常持续约 12 小时。然而，考虑到中期妊娠时宫颈条件不成熟，适当延长 DBC 的放置时间至 24 小时将有利于宫颈成熟，减少扩张和排空的机会。
