Hase Eliane Azeka, Amaral Amanda, Peres Stela Verzinhasse, Francisco Rossana Pulcineli Vieira
Department of Obstetrics and Gynecology of the Hospital das Clínicas of the Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Department of Obstetrics and Gynecology of the Hospital das Clínicas of the Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Clinics (Sao Paulo). 2025 Mar 15;80:100616. doi: 10.1016/j.clinsp.2025.100616. eCollection 2025.
This study aimed to determine the normal range of fetal weight by ultrasound in pregnant women followed at the Obstetric Clinic of the Hospital das Clínicas of the Faculty of Medicine, University of São Paulo.
This retrospective cohort study included singleton pregnant women without associated maternal diseases, at 15-41 weeks of gestation, who underwent their last ultrasound up to 7 days before birth. Fetal parameters analyzed for the normal range were biparietal diameter, femur length, head and abdominal circumference. 3rd, 10th, 50th, 90th, and 97th weight percentiles were determined for each gestational age. Newborns were classified by birth weight as Small (SGA), Appropriate (AGA), or Large (LGA) for gestational age.
Among 837 women admitted without maternal diseases, 136 were included and 379 examinations performed at 15-41 weeks of gestation. Multiple linear regression models were generated to develop the normal range of fetal weight. Three equations were selected, and six normal ranges were created considering the total population and stratified by fetal sex. Weight estimates were calculated for the 3rd, 10th, 50th, 90th, and 97th percentiles for each gestational age. Among the 136 newborns, 107 (78.7 %) were classified as AGA, 23 (16.9 %) as SGA, and 6 (4.4 %) as LGA.
The normal range of the fetal weight determined by ultrasound in this population showed a good correlation with gestational age, enabling the fetal weight gain pattern evaluation. The equation based on four parameters, including days before birth, presented the lowest percentage error variation to estimate the normal range.
本研究旨在确定圣保罗大学医学院临床医院产科门诊所随访孕妇经超声测量的胎儿体重正常范围。
这项回顾性队列研究纳入了妊娠15 - 41周、无相关母体疾病的单胎孕妇,她们在出生前7天内接受了最后一次超声检查。分析用于确定正常范围的胎儿参数有双顶径、股骨长度、头围和腹围。确定了每个孕周的第3、10、50、90和97体重百分位数。新生儿按出生体重分为小于胎龄儿(SGA)、适于胎龄儿(AGA)或大于胎龄儿(LGA)。
在837名无母体疾病的入院妇女中,纳入了136名,并在妊娠15 - 41周进行了379次检查。生成了多元线性回归模型以确定胎儿体重的正常范围。选择了三个方程,并考虑总体人群和按胎儿性别分层创建了六个正常范围。计算了每个孕周第3、10、50、90和97百分位数的体重估计值。在136名新生儿中,107名(78.7%)被分类为AGA,23名(16.9%)为SGA,6名(4.4%)为LGA。
该人群经超声确定的胎儿体重正常范围与孕周显示出良好的相关性,有助于评估胎儿体重增加模式。基于包括出生前天数在内的四个参数的方程在估计正常范围时呈现出最低的百分比误差变化。