Castillo Alyssa M, Tata Asha L, Seung Hyunuk, Bathula Matt, Goel Nidhi, Heavner Mojdeh S, Kelly Sean, So Jennifer Y, Grover Brian
Texas A&M Irma Lerma Rangel College of Pharmacy Kingsville Campus, Kingsville, TX, USA.
University of Maryland Medical Center, Baltimore, MD, USA.
Hosp Pharm. 2025 Mar 12:00185787251324873. doi: 10.1177/00185787251324873.
Sleep in the hospital is often disrupted by modifiable factors. When addressing poor sleep in the hospital, non-pharmacologic strategies should be utilized initially; however, pharmacologic therapies are often prescribed first. The objective of this initiative was to determine if pharmacist-led initiation of a sleep promotion order set improved quality of inpatient sleep. This was a prospective, single-center, before-and-after quality improvement project. Patients admitted to the adult internal medicine service with a pharmacologic sleep aid ordered were considered for inclusion. Pharmacists conducted baseline sleep assessments using the Modified Richards Campbell Sleep Questionnaire (mRCSQ), then recommended initiation of the sleep promotion order set. A second mRCSQ was conducted 2 to 5 nights after order set initiation. The mean difference in mRCSQ for individual patients before and after sleep promotion were compared. Fifty-three patients completed both baseline and follow-up mRCSQ surveys. The average mRCSQ score before sleep promotion was 55.8 and the average score after sleep promotion was 56.8 with a subject paired difference of 1.0; = .8. Individual components of the mRCSQ survey were compared and not found to have significant differences. Implementation of the sleep promotion order set did not result in a significant improvement in patient-reported sleep. This study was marked by significant limitations including difficulty with patient comprehension of the mRCSQ sleep assessment tool, lack of assessment of adherence to the order set, and variability in where in patient clinical course sleep assessments were performed. Despite the findings of this project, further evaluation should be made into the ideal sleep assessment tool for an internal medicine patient population. Medical teams should continue to make an interdisciplinary effort to address modifiable risk factors to optimize sleep in the hospital and limit prescribing of pharmacologic sleep aids.
医院中的睡眠常常受到可改变因素的干扰。在解决医院睡眠质量差的问题时,应首先采用非药物策略;然而,药物治疗却常常被优先开具。本倡议的目的是确定由药剂师主导启动睡眠促进医嘱集是否能改善住院患者的睡眠质量。这是一项前瞻性、单中心、前后对照的质量改进项目。入住成人内科且开具了药物助眠剂的患者被纳入研究。药剂师使用改良版理查兹·坎贝尔睡眠问卷(mRCSQ)进行基线睡眠评估,然后建议启动睡眠促进医嘱集。在医嘱集启动后的2至5个晚上进行第二次mRCSQ评估。比较了个体患者在睡眠促进前后mRCSQ的平均差异。53名患者完成了基线和随访的mRCSQ调查。睡眠促进前mRCSQ的平均得分是55.8,睡眠促进后的平均得分是56.8,个体配对差异为1.0;P = 0.8。对mRCSQ调查的各个组成部分进行比较,未发现有显著差异。睡眠促进医嘱集的实施并未使患者报告的睡眠状况得到显著改善。本研究存在显著局限性,包括患者对mRCSQ睡眠评估工具理解困难、未评估对医嘱集的依从性以及睡眠评估在患者临床病程中的实施位置存在差异。尽管有本项目的研究结果,但仍应进一步评估针对内科患者群体的理想睡眠评估工具。医疗团队应继续进行跨学科努力,以解决可改变的风险因素,优化医院睡眠并限制药物助眠剂的处方。