De Vizia B, Poggi V, Vajro P, Cucchiara S, Acampora A
J Pediatr. 1985 Jul;107(1):75-8. doi: 10.1016/s0022-3476(85)80618-1.
Among 10 children with giardiasis, eight had iron deficiency; iron deficiency anemia was the main complaint in three. Evaluation of iron absorption by the oral iron load test demonstrated a subnormal response (i.e., increase in serum iron levels of less than 100 micrograms/dl) in all eight patients with iron deficiency. In contrast, in two iron-sufficient patients with giardiasis the response to an oral iron load was normal. Xylose absorption was abnormal in five of the 10 patients. After metronidazole dosing, iron absorption became normal in seven patients but remained abnormal in one patient, who also had IgA deficiency. Xylose absorption became normal in all five patients who underwent a second test, but remained abnormal in the patient with IgA deficiency. Concomitant morphologic-studies of jejunal biopsy material from these patients revealed moderate changes in the intestinal mucosa of two patients. We conclude that malabsorption of iron is a complication of giardiasis.
在10例贾第虫病患儿中，8例有缺铁情况；缺铁性贫血是3例的主要症状。通过口服铁负荷试验评估铁吸收情况，结果显示所有8例缺铁患者的反应均低于正常水平（即血清铁水平升高不足100微克/分升）。相比之下，2例铁充足的贾第虫病患者对口服铁负荷的反应正常。10例患者中有5例木糖吸收异常。甲硝唑给药后，7例患者的铁吸收恢复正常，但1例患者仍异常，该患者也有IgA缺乏症。接受第二次检测的5例患者木糖吸收均恢复正常，但IgA缺乏症患者仍异常。对这些患者空肠活检材料进行的形态学研究显示，2例患者的肠道黏膜有中度改变。我们得出结论，铁吸收不良是贾第虫病的一种并发症。
