贾第虫病中空肠黏膜的细菌定植

Bacterial colonization of jejunal mucosa in giardiasis.

作者信息

Tomkins A M, Wright S G, Drasar B S, James W P

出版信息

Trans R Soc Trop Med Hyg. 1978;72(1):33-6. doi: 10.1016/0035-9203(78)90294-8.

Abstract

Nine of 14 cases of giardiasis and severe malabsorption were found to have numerous bacteria adjacent to the mucosa and within luminal fluid samples from the upper jejunum. Three species of enterobacteria (Klebsiella pneumoniae, Enterobacter cloacae and E. hafniae) were cultured from eight patients and from only one were Bacteroides isolated. Enterobacteria were not cultured from seven of eight patients who had giardiasis but only mild malabsorption (of xylose only) nor from seven patients without malabsorption. Intestinal colonization by enterobacteria may make an important contribution to the development of malabsorption in patients with giardiasis.

摘要

在14例贾第虫病合并严重吸收不良的病例中，发现有9例患者空肠上段黏膜附近及肠腔液样本中有大量细菌。从8例患者中培养出三种肠杆菌（肺炎克雷伯菌、阴沟肠杆菌和哈夫尼亚菌），仅从1例患者中分离出拟杆菌。在8例仅有轻度吸收不良（仅木糖吸收不良）的贾第虫病患者中，有7例未培养出肠杆菌，7例无吸收不良的患者中也未培养出肠杆菌。肠杆菌在肠道的定植可能对贾第虫病患者吸收不良的发展起重要作用。