Decoding eosinophils: biological insights hidden in plain sight?
作者信息
Dunn Julia L M, Spencer Lisa A
机构信息
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Colorado Anschutz Medical Campus, 13001 E 17th Place, Aurora, CO 80045, USA.
Digestive Health Institute, Children's Hospital Colorado, 13123 E 16th Ave, Aurora, CO 80045, USA.
出版信息
J Leukoc Biol. 2025 Apr 23;117(4). doi: 10.1093/jleuko/qiaf030.
Abstract
摘要
相似文献
1
Decoding eosinophils: biological insights hidden in plain sight?解读嗜酸性粒细胞：隐藏在眼前的生物学见解？
J Leukoc Biol. 2025 Apr 23;117(4). doi: 10.1093/jleuko/qiaf030.
2
Limited clinical role of blood eosinophil levels in early life atopic disease: A mother-child cohort study.生命早期特应性疾病中血液嗜酸性粒细胞水平的临床作用有限：一项母子队列研究。
Pediatr Allergy Immunol. 2023 Nov;34(11):e14050. doi: 10.1111/pai.14050.
3
Enhanced Siglec-8 and HLA-DR and reduced CRTH2 surface expression highlight a distinct phenotypic signature of circulating eosinophils in atopic dermatitis.增强的唾液酸结合免疫球蛋白样凝集素8（Siglec-8）和人类白细胞抗原DR（HLA-DR）以及降低的半胱氨酰白三烯受体2（CRTH2）表面表达凸显了特应性皮炎中循环嗜酸性粒细胞独特的表型特征。
J Leukoc Biol. 2025 Apr 23;117(4). doi: 10.1093/jleuko/qiaf023.
4
Urinary eosinophil-derived neurotoxin concentrations in patients with atopic dermatitis: a useful clinical marker for disease activity.特应性皮炎患者尿中嗜酸性粒细胞衍生神经毒素浓度：疾病活动度的有用临床标志物。
Allergol Int. 2007 Dec;56(4):433-8. doi: 10.2332/allergolint.O-07-489. Epub 2007 Nov 1.
5
Blood eosinophils, eosinophil-derived proteins, and leukotriene C4 generation in relation to bronchial hyperreactivity in children with atopic dermatitis.特应性皮炎患儿血液嗜酸性粒细胞、嗜酸性粒细胞衍生蛋白及白三烯C4生成与支气管高反应性的关系
Allergy. 1995 Feb;50(2):126-32. doi: 10.1111/j.1398-9995.1995.tb05068.x.
6
Dermal eosinophils in atopic dermatitis undergo cytolytic degeneration.特应性皮炎中的皮肤嗜酸性粒细胞会发生溶细胞性变性。
J Allergy Clin Immunol. 1997 May;99(5):683-92. doi: 10.1016/s0091-6749(97)70031-9.
7
Eosinophils in atopic dermatitis.特应性皮炎中的嗜酸性粒细胞。
Allergy. 1989;44 Suppl 9:20-6.
8
Elevated blood eosinophils in early infancy are predictive of atopic dermatitis in children with risk for atopy.婴儿早期血液嗜酸性粒细胞升高可预测有特应性风险儿童的特应性皮炎。
Pediatr Allergy Immunol. 2016 Nov;27(7):702-708. doi: 10.1111/pai.12607. Epub 2016 Aug 9.
9
Blood eosinophilia in atopic dermatitis.特应性皮炎中的血液嗜酸性粒细胞增多症。
Clin Exp Dermatol. 1990 Jul;15(4):264-6. doi: 10.1111/j.1365-2230.1990.tb02086.x.
10
Contribution of selectin ligands to eosinophil recruitment into the skin of patients with atopic dermatitis.选择素配体在嗜酸性粒细胞募集至特应性皮炎患者皮肤中的作用。
Eur J Immunol. 2002 May;32(5):1274-81. doi: 10.1002/1521-4141(200205)32:5<1274::AID-IMMU1274>3.0.CO;2-Q.
本文引用的文献
1
Enhanced Siglec-8 and HLA-DR and reduced CRTH2 surface expression highlight a distinct phenotypic signature of circulating eosinophils in atopic dermatitis.增强的唾液酸结合免疫球蛋白样凝集素8（Siglec-8）和人类白细胞抗原DR（HLA-DR）以及降低的半胱氨酰白三烯受体2（CRTH2）表面表达凸显了特应性皮炎中循环嗜酸性粒细胞独特的表型特征。
J Leukoc Biol. 2025 Apr 23;117(4). doi: 10.1093/jleuko/qiaf023.
2
Single-cell RNA sequencing of human blood eosinophils reveals plasticity and absence of canonical cell subsets.人类血液嗜酸性粒细胞的单细胞RNA测序揭示了可塑性和经典细胞亚群的缺失。
Allergy. 2025 Feb;80(2):570-574. doi: 10.1111/all.16213. Epub 2024 Jun 27.
3
Single-cell RNA-sequencing of human eosinophils in allergic inflammation in the esophagus.单细胞 RNA 测序在食管过敏炎症中对人类嗜酸性粒细胞的研究。
J Allergy Clin Immunol. 2024 Oct;154(4):974-987. doi: 10.1016/j.jaci.2024.05.029. Epub 2024 Jun 11.
4
Single cell RNA sequencing of human eosinophils from nasal polyps reveals eosinophil heterogeneity in chronic rhinosinusitis tissue.单细胞 RNA 测序分析鼻息肉中的人嗜酸性粒细胞揭示慢性鼻-鼻窦炎组织中嗜酸性粒细胞的异质性。
J Allergy Clin Immunol. 2024 Oct;154(4):952-964. doi: 10.1016/j.jaci.2024.05.014. Epub 2024 May 24.
5
Eosinophils as potential biomarkers in respiratory viral infections.嗜酸性粒细胞作为呼吸道病毒感染的潜在生物标志物。
Front Immunol. 2023 Jul 6;14:1170035. doi: 10.3389/fimmu.2023.1170035. eCollection 2023.
6
Atopic dermatitis endotypes and implications for targeted therapeutics.特应性皮炎的表型和对靶向治疗的影响。
J Allergy Clin Immunol. 2019 Jan;143(1):1-11. doi: 10.1016/j.jaci.2018.10.032.
7
Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD.血液嗜酸性粒细胞作为哮喘和 COPD 治疗选择的生物标志物。
Curr Drug Targets. 2018;19(16):1882-1896. doi: 10.2174/1389450119666180212120012.
8
Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma.血液嗜酸性粒细胞计数是一种有用的生物标志物，可用于识别患有严重嗜酸性粒细胞性哮喘的患者。
Ann Am Thorac Soc. 2014 May;11(4):531-6. doi: 10.1513/AnnalsATS.201310-354OC.
9
Increased expression of CRTH2 on eosinophils in allergic skin diseases.变应性皮肤病中嗜酸性粒细胞上CRTH2表达增加。
J Eur Acad Dermatol Venereol. 2010 Jan;24(1):75-6. doi: 10.1111/j.1468-3083.2009.03267.x. Epub 2009 Apr 8.
10
Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia.人类外周血嗜酸性粒细胞的异质性：与嗜酸性粒细胞增多症的程度和来源相关的细胞密度和细胞毒性能力的变异性。
Int Arch Allergy Appl Immunol. 1983;72(4):336-46. doi: 10.1159/000234893.
Zotero 插件