Uehara M, Izukura R, Sawai T
Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.
Clin Exp Dermatol. 1990 Jul;15(4):264-6. doi: 10.1111/j.1365-2230.1990.tb02086.x.
Blood eosinophil levels were examined in 200 (100 mild and 100 severe) patients with atopic dermatitis. Eosinophil levels roughly correlated with disease severity. However, the pattern of eosinophilia was not homogeneous. Very high eosinophil counts were common in severe cases of atopic dermatitis who had a personal or family history of respiratory atopy, while normal or moderately elevated eosinophil values were obtained in severe cases of 'pure' atopic dermatitis who had neither personal nor family history of respiratory atopy. It is suggested that disease severity and personal or family history of respiratory atopy are important factors in determining high blood eosinophil levels in atopic dermatitis.
对200例（100例轻度和100例重度）特应性皮炎患者的血液嗜酸性粒细胞水平进行了检测。嗜酸性粒细胞水平大致与疾病严重程度相关。然而，嗜酸性粒细胞增多的模式并不一致。在有呼吸道特应性个人或家族史的重度特应性皮炎病例中，嗜酸性粒细胞计数非常高很常见，而在既无呼吸道特应性个人史也无家族史的“单纯”重度特应性皮炎病例中，嗜酸性粒细胞值正常或中度升高。提示疾病严重程度以及呼吸道特应性的个人或家族史是决定特应性皮炎患者血液嗜酸性粒细胞水平升高的重要因素。
