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儿童和青少年腹痛障碍患者睡眠障碍的范围综述

A Scoping Review of Sleep Disturbances in Children and Adolescents with Abdominal Pain Disorders.

作者信息

Friesen Hunter J, Singh Neha, Schurman Jennifer V, Deacy Amanda D, Friesen Craig A, Colombo Jennifer M

机构信息

Department of Pediatrics, Children's Mercy Kansas City, Kansas City, MO, USA.

Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS, USA.

出版信息

Pediatric Health Med Ther. 2025 Mar 13;16:67-73. doi: 10.2147/PHMT.S482343. eCollection 2025.

Abstract

OBJECTIVE/PURPOSE/AIM: Sleep disturbances have been implicated as contributors to chronic pain. We undertook this review to assess the current literature regarding sleep disturbances in youth with chronic abdominal pain. We assessed studies evaluating prevalence, pathophysiology, and/or outcomes to identify gaps in knowledge and to determine whether there is an evidential basis for sleep interventions in this population.

MATERIALS AND METHODS

Utilizing Google Scholar, Pub Med, SCOPUS, and Embase, we searched using the terms "sleep disturbances" AND ("abdominal pain"/exp OR "abdominal pain") AND ([adolescent]/lim OR [school]/lim). Articles were included if they contained data regarding sleep disturbance prevalence, pathophysiology, or relationships to outcome. After two independent review, 32 manuscripts were included in this review.

RESULTS

Based on their high prevalence (19-75% of abdominal pain cohorts), there is sufficient evidence to recommend routine screening for sleep disturbances in youth with chronic abdominal pain. There is a broad range of negative physiologic and emotional effects of sleep deprivation.

CONCLUSION

Sleep disturbances are common in youth with chronic abdominal pain. Sleep interventions are appropriate when disturbances are identified though it is not yet known the degree to which these interventions will affect the pain experience and resultant disability. Future studies should focus on evaluation of specific sleep interventions on patient outcomes.

摘要

目的

睡眠障碍被认为是慢性疼痛的促成因素。我们进行这项综述以评估当前有关慢性腹痛青少年睡眠障碍的文献。我们评估了评估患病率、病理生理学和/或结局的研究,以找出知识空白,并确定针对该人群进行睡眠干预是否有证据基础。

材料与方法

利用谷歌学术、PubMed、SCOPUS和Embase,我们使用“睡眠障碍”以及(“腹痛”/扩展或“腹痛”)以及([青少年]/限定或[学校]/限定)进行搜索。如果文章包含有关睡眠障碍患病率、病理生理学或与结局关系的数据,则将其纳入。经过两轮独立评审,本综述纳入了32篇手稿。

结果

基于其高患病率(慢性腹痛队列的19%-75%),有充分证据建议对慢性腹痛青少年进行睡眠障碍的常规筛查。睡眠剥夺会产生广泛的负面生理和情绪影响。

结论

睡眠障碍在慢性腹痛青少年中很常见。当发现睡眠障碍时,睡眠干预是合适的,不过目前尚不清楚这些干预措施会在多大程度上影响疼痛体验和由此导致的残疾。未来的研究应侧重于评估特定睡眠干预对患者结局的影响。

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本文引用的文献

1
Importance of sleep quality in functional abdominal pain disorder in pediatric patients.
Sleep Biol Rhythms. 2021 Jul 23;20(1):81-85. doi: 10.1007/s41105-021-00342-9. eCollection 2022 Jan.
2
Sleep Problems in Pediatric Disorders of Gut-Brain Interaction: A Systematic Review.
J Pediatr Psychol. 2023 Sep 20;48(9):778-786. doi: 10.1093/jpepsy/jsad047.
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A Cross-Sectional Study of Sleep Disturbances in Children and Adolescents With Abdominal Pain-Associated Disorders of Gut-Brain Interaction.
Clin Pediatr (Phila). 2024 Jun;63(5):697-702. doi: 10.1177/00099228231187226. Epub 2023 Jul 17.
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Impact of Sleep Disturbance on Fatigue, Nausea, and Pain: Mediating Role of Depressive Symptoms Among Youth With Disorders of Gut-Brain Interaction.
J Pediatr Gastroenterol Nutr. 2023 Oct 1;77(4):468-473. doi: 10.1097/MPG.0000000000003887. Epub 2023 Sep 20.
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