Kim Hyun Jin
Department of Pediatrics, Chungnam National University Hospital, Daejeon, 35015 South Korea.
Sleep Biol Rhythms. 2021 Jul 23;20(1):81-85. doi: 10.1007/s41105-021-00342-9. eCollection 2022 Jan.
The incidence of sleep problems is increasing in children, and they are thought to contribute to pain in functional abdominal pain disorder (FAPD). In this study, we aimed to evaluate the pattern of sleep disturbance in children with FAPD and identify the associated factors. We retrospectively analyzed patients aged 12-18 years who were diagnosed with FAPD based on the Rome IV criteria. To assess sleep problems, we used the Korean version of the Pittsburgh Sleep Quality Index (PSQI-K). To evaluate factors associated with sleep disturbances, we used the odds ratios (OR) estimated in logistic regression models. Among the 66 patients evaluated, 57.6% (38/66) had a total PSQI-K score > 5, indicating a significant disturbance in sleep, 52.6% (20/38) had irritable bowel syndrome (IBS), and 47.4% (18/38) had functional abdominal pain-not otherwise specified. The mean PSQI-K score was 7.2 ± 6.0, and longer sleep onset latency was noted (26.33 ± 19.44 min) in all patients than healthy controls. Almost all PSQI-K subscales scores were elevated in patients with IBS. In univariate analysis, abdominal pain score > 7 and IBS were associated with poor sleep quality. In multivariate analysis, only IBS was associated with sleep disturbance. A relatively large proportion of patients with FAPD had sleep problems and these were more common in patients with IBS. Thus, interventions for improving sleep quality should also be considered in patients with FAPD with severe abdominal pain and IBS.
儿童睡眠问题的发生率正在上升，并且人们认为这些问题会导致功能性腹痛障碍（FAPD）中的疼痛。在本研究中，我们旨在评估FAPD患儿的睡眠障碍模式，并确定相关因素。我们回顾性分析了根据罗马IV标准被诊断为FAPD的12至18岁患者。为了评估睡眠问题，我们使用了匹兹堡睡眠质量指数韩国版（PSQI-K）。为了评估与睡眠障碍相关的因素，我们使用了逻辑回归模型中估计的优势比（OR）。在评估的66例患者中，57.6%（38/66）的PSQI-K总分>5，表明睡眠存在显著障碍，52.6%（20/38）患有肠易激综合征（IBS），47.4%（18/38）患有未另行指定的功能性腹痛。所有患者的PSQI-K平均得分为7.2±6.0，且与健康对照组相比，入睡潜伏期更长（26.33±19.44分钟）。IBS患者几乎所有的PSQI-K分量表得分均升高。在单因素分析中，腹痛评分>7和IBS与睡眠质量差有关。在多因素分析中，只有IBS与睡眠障碍有关。FAPD患者中相当大比例存在睡眠问题，且这些问题在IBS患者中更为常见。因此，对于伴有严重腹痛的FAPD患者和IBS患者，也应考虑采取改善睡眠质量的干预措施。
