红细胞分布宽度对颅内出血死亡率的预后价值：一项系统评价和荟萃分析。
The prognostic value of red blood cell distribution width for mortality in intracranial hemorrhage: A systematic review and meta-analysis.
作者信息
Zhang Ping, Chen Ying, Zhou Jian, Li Miao, Wang Yanxin, Wang Yan, Ji Runzhi, Chen Zhenggang
机构信息
Department of Nephrology, The First Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Nursing Department, First Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
出版信息
Medicine (Baltimore). 2025 Mar 14;104(11):e41487. doi: 10.1097/MD.0000000000041487.
BACKGROUND
Some studies have reported conflicting results regarding the prognostic value of red blood cell distribution width (RDW) for patients with intracranial hemorrhage (ICH). This meta-analysis aims to investigate the association between RDW and all-cause mortality in ICH.
METHODS
We systematically searched the following databases, including PubMed, EMBASE, Cochrane library, and Web of Science, for all studies assessing the prognostic value of mortality in patients with ICH from inception to December 2023. We calculated pooled odds ratios (ORs) and 95% confidence intervals (CIs).
RESULTS
A total of 7 studies evaluated the association of RDW and all-cause mortality. A higher RDW levels were significantly associated with all-cause mortality (OR = 1.52; 95% CI = 1.22 to 1.89; P = .0002; I2 = 76%).
CONCLUSION
Therefore, RDW is a valuable prognostic marker for the risk of all-cause mortality in patients with intracranial hemorrhage.
背景
一些研究报告了红细胞分布宽度（RDW）对颅内出血（ICH）患者预后价值的相互矛盾的结果。本荟萃分析旨在研究RDW与ICH患者全因死亡率之间的关联。
方法
我们系统检索了以下数据库，包括PubMed、EMBASE、Cochrane图书馆和Web of Science，以查找所有评估自开始至2023年12月ICH患者死亡率预后价值的研究。我们计算了合并比值比（OR）和95%置信区间（CI）。
结果
共有7项研究评估了RDW与全因死亡率的关联。较高的RDW水平与全因死亡率显著相关（OR = 1.52；95% CI = 1.22至1.89；P = 0.0002；I2 = 76%）。
结论
因此，RDW是颅内出血患者全因死亡风险的有价值的预后标志物。
Zotero 插件