Rhew Isaac C, Graupensperger Scott, Martinez Griselda, Lee Christine M
Center for the Study of Health and Risk Behaviors, Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
Center for the Study of Health and Risk Behaviors, Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
Addict Behav. 2025 Jul;166:108326. doi: 10.1016/j.addbeh.2025.108326. Epub 2025 Mar 12.
The current study examined whether young adults showing a pattern of greater substance use on months when experiencing greater levels of depressive symptoms showed long-term hazardous alcohol and cannabis use and elevated depressive symptoms. Data were from 772 young adults in Washington State (mean age = 21.1 years, SD = 1.7; 57 % female). For 24 consecutive months, surveys asked about past-month depressive symptoms and typical number of alcoholic drinks per week and typical number hours high on cannabis per week. Participants completed a survey 30 months after baseline that included measures of depressive symptoms and hazardous alcohol and cannabis use. Multilevel models showed substantial variability in monthly within-person associations of depressive symptoms with alcohol and cannabis use across individuals during the first 24 months. On months when experiencing increased depressive symptoms compared to their average, some young adults used more alcohol or cannabis and some used less. When linking outcomes at 30-month follow-up to person-specific slopes extracted from the multilevel models, results showed that young adults who tended to drink more or use more cannabis when they experienced more depressive symptoms than their average reported greater levels of hazardous alcohol and cannabis use at 30-month follow-up, respectively. Person-specific slopes were not associated with 30-month depressive symptoms. Although there was substantial variability in within-person monthly associations, findings suggest that young adults showing short-term patterns consistent with increased alcohol and cannabis use to regulate depressive symptoms may benefit from prevention and intervention efforts aimed at decreasing risk of longer-term problematic substance use.
在经历较高水平抑郁症状的月份里表现出更多物质使用模式的年轻人，是否会出现长期有害的酒精和大麻使用以及抑郁症状加剧的情况。数据来自华盛顿州的772名年轻人（平均年龄=21.1岁，标准差=1.7；57%为女性）。在连续24个月的时间里，调查询问了过去一个月的抑郁症状、每周饮用酒精饮料的典型数量以及每周吸食大麻的典型时长。参与者在基线后30个月完成了一项调查，其中包括抑郁症状、有害酒精和大麻使用的测量。多层次模型显示，在最初的24个月里，个体之间每月抑郁症状与酒精和大麻使用的个体内关联存在很大差异。与平均水平相比，在经历抑郁症状增加的月份里，一些年轻人饮酒或吸食大麻更多，而一些年轻人则更少。当将30个月随访的结果与从多层次模型中提取的个体特定斜率联系起来时，结果显示，在经历比平均水平更多的抑郁症状时倾向于饮用更多酒精或使用更多大麻的年轻人，在30个月随访时分别报告了更高水平的有害酒精和大麻使用。个体特定斜率与30个月时的抑郁症状无关。尽管个体内每月关联存在很大差异，但研究结果表明，表现出与增加酒精和大麻使用以调节抑郁症状相一致的短期模式的年轻人，可能会从旨在降低长期物质使用问题风险的预防和干预措施中受益。
