Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.
J Stud Alcohol Drugs. 2023 Nov;84(6):913-920. doi: 10.15288/jsad.22-00431. Epub 2023 Aug 30.
Experiencing negative substance use consequences may deter future use, alter patterns of substance use (e.g., substituting one substance for another, combining substances), or point to a sustained pattern of engaging in heavy or frequent use. We used monthly data to examine relationships between negative alcohol and cannabis use consequences experienced in one month and changes in use the following month.
Data were from 508 individuals (59% female; ages 18-23 years at enrollment) who were surveyed monthly for 2 years and used both alcohol and cannabis during the study period. Multilevel models assessed within-person associations between monthly fluctuations in substance-related negative consequences and the next month's substance use (i.e., typical drinks per week, cannabis use frequency, and simultaneous alcohol and cannabis/marijuana [SAM] use), controlling for the prior month's substance use.
Positive associations were found between alcohol consequences and the following month's alcohol use and between cannabis consequences and subsequent cannabis use, although only the cannabis association was statistically significant. There was little evidence of effects of cannabis consequences on the next month's alcohol use or alcohol consequences on the next month's cannabis use. Cannabis consequences had a positive and statistically significant association with the next month's SAM use. Within-substance positive associations were strongest for physical alcohol consequences and cannabis consequences of low motivation, memory problems, and trouble breathing.
Experiencing negative cannabis use consequences predicted more frequent cannabis use and greater chance of SAM use 1 month later. Results point to negative consequences, along with prior use, indicating risk for future use.
体验到负面的物质使用后果可能会阻止未来的使用,改变物质使用模式(例如,用一种物质代替另一种物质,混合使用物质),或者表明持续大量或频繁使用的模式。我们使用月度数据来检验一个月内经历的负面酒精和大麻使用后果与下一个月使用情况之间的关系。
数据来自 508 名个体(59%为女性;入组时年龄为 18-23 岁),他们在两年内每月接受调查,并在研究期间同时使用酒精和大麻。多层次模型评估了物质相关负面后果在月度波动与下一个月物质使用之间的个体内关联(即每周典型饮酒量、大麻使用频率和同时使用酒精和大麻/大麻[SAM]),同时控制了前一个月的物质使用情况。
发现酒精后果与下一个月的酒精使用之间以及大麻后果与随后的大麻使用之间存在正相关,尽管只有大麻关联具有统计学意义。几乎没有证据表明大麻后果对下一个月的酒精使用或酒精后果对下一个月的大麻使用有影响。大麻后果与下一个月的 SAM 使用呈正相关且具有统计学意义。在同一物质内,身体酒精后果和低动机、记忆问题和呼吸困难等低动机的大麻后果与下一个月的使用之间存在最强的正相关。
体验到负面的大麻使用后果预示着下一个月更频繁的大麻使用和更大的 SAM 使用机会。结果表明,负面后果以及之前的使用情况,预示着未来使用的风险。