Gurevich Vsevolod V
Department of Pharmacology, Vanderbilt University, Nashville, TN 27232, USA.
Trends Biochem Sci. 2025 May;50(5):374-375. doi: 10.1016/j.tibs.2025.02.003. Epub 2025 Mar 17.
The cell is a dynamic system where millions of molecules of thousands different kinds act within a complex network with numerous feedback loops. Because we cannot pursue many targets simultaneously, 'big data' rarely yield useful leads. Comprehensive models can place the snippets obtained in simplified experimental conditions into a coherent picture.
细胞是一个动态系统，其中数以千计的不同种类的数百万个分子在一个具有众多反馈回路的复杂网络中发挥作用。由于我们无法同时追踪多个目标，“大数据”很少能产生有用的线索。综合模型可以将在简化实验条件下获得的片段整合为一幅连贯的图景。
