Chun Kyeong-Hyeon, Kim Hyun-Jin, Kang Dae Ryong, Kim Jang Young, Kim Wonjin, Jeong Yong Whi, Han Seung Hwan, Koh Kwang Kon
Division of Cardiology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
Korean J Intern Med. 2025 Mar;40(2):262-274. doi: 10.3904/kjim.2024.288. Epub 2025 Mar 1.
BACKGROUND/AIMS: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted global health, exacerbated metabolic health issues, and altered lifestyle behaviors. This study examined the sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome using data from the Korea National Health and Nutrition Examination Survey (KNHANES).
Data from the KNHANES VII (2018) and VIII (2019-2021), including 15,499 participants, were analyzed. The study population was stratified by sex, and further subdivisions were conducted based on the timeframe relative to the COVID-19 outbreak. Variables such as age, education level, household income, smoking status, and high-risk drinking were analyzed to assess their influence on the prevalence of metabolic syndrome.
The overall prevalence of metabolic syndrome significantly increased from 28.11% before the outbreak to 29.69% after the outbreak. Both males and females reported significant increases in waist circumference and fasting glucose levels. Age and education level differentially influenced the prevalence of metabolic syndrome between the sex. Smoking was significantly associated with increased prevalence in males, whereas high-risk drinking was associated with increased prevalence in males and decreased prevalence in females.
The COVID-19 pandemic has significantly increased the prevalence of metabolic syndrome with notable sex-specific differences. These findings highlight the need for sex-specific public health interventions to mitigate the impact of the pandemic on metabolic health.
背景/目的：2019年冠状病毒病（COVID-19）大流行对全球健康产生了重大影响，加剧了代谢健康问题，并改变了生活方式行为。本研究利用韩国国家健康与营养检查调查（KNHANES）的数据，研究了COVID-19疫情对代谢综合征发病率的性别特异性影响。
分析了KNHANES VII（2018年）和VIII（2019 - 2021年）的数据，包括15499名参与者。研究人群按性别分层，并根据与COVID-19疫情相关的时间框架进一步细分。分析了年龄、教育水平、家庭收入、吸烟状况和高风险饮酒等变量，以评估它们对代谢综合征患病率的影响。
代谢综合征的总体患病率从疫情前的28.11%显著增加到疫情后的29.69%。男性和女性的腰围和空腹血糖水平均显著增加。年龄和教育水平对不同性别的代谢综合征患病率有不同影响。吸烟与男性患病率增加显著相关，而高风险饮酒与男性患病率增加和女性患病率降低相关。
COVID-19大流行显著增加了代谢综合征的患病率，且存在明显的性别特异性差异。这些发现凸显了针对性别的公共卫生干预措施的必要性，以减轻大流行对代谢健康的影响。
