Abdulraheem Ahmad, Shukri Dania, Altork Nadera, Afzal Usman, Abu-Rumaileh Mohammed, Meighani Alireza
Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA.
Internal Medicine, Jordan University Hospital, Amman, JOR.
Cureus. 2025 Feb 16;17(2):e79105. doi: 10.7759/cureus.79105. eCollection 2025 Feb.
Colonoscopy (CLN) is a common procedure for colon cancer screening and diagnosing various conditions. Acute cholecystitis (AC), though rare, has been reported as a complication. We present a 66-year-old female on semaglutide for obesity who developed AC within 72 hours post-CLN. Considering the increasing use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and their impact on gallbladder motility, these medications may contribute to this complication. Future research is crucial to investigate whether a washout period for GLP-1 agonists before CLN is needed to reduce the risk of AC, if such a risk exists.
结肠镜检查（CLN）是结肠癌筛查和诊断各种病症的常见程序。急性胆囊炎（AC）虽然罕见，但已被报告为一种并发症。我们报告一名66岁肥胖女性，在接受CLN后72小时内发生了AC。考虑到胰高血糖素样肽-1受体激动剂（GLP-1 RAs）的使用日益增加及其对胆囊运动的影响，这些药物可能导致这种并发症。如果存在这种风险，未来的研究对于调查在CLN前是否需要GLP-1激动剂的洗脱期以降低AC风险至关重要。
