Yan Yunling, Lu Sha, Wu Shan, Wang Kai, Xu Yunjing, Zhan Kui, Zeng Ying, Man MaoQiang, Yang Bin, Liu Zhenfeng
Southern Medical University Dermatology Hospital, Lujing Road, No. 2, Yuexiu District, Guangzhou, Guangdong Province, China.
Department of Dermatology, Sun Yet-Sen Memorial Hospital (Second Affiliated Hospital) of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Lasers Med Sci. 2025 Mar 19;40(1):148. doi: 10.1007/s10103-025-04414-x.
Although many home-used intense pulsed light (IPL) are available for hair removal, whether these devices exhibit comparable efficacy and safety to those IPL used at hospitals is unknown. Therefore, we compared here the efficacy and safety of a home-used UI04 IPL freezing point hair removal device with a Broadband Light (BBL) intense pulsed light hair removal device for hair removal. A total of 84 participants were enrolled from our outpatient clinic. In each participant, the right and the left sides of the axilla, calf, or forearm were randomly assigned to either the observation side treated with a UI04 IPL hair removal device or control side treated with a BBL device for 3 months and were followed up for 3 months. Our results showed that 78 out of 84 (87.6%) patients completed the study. After 1-month treatment, the effective rate of hair removal was significantly higher on the observation side than on the control side (P = 0.001). After 3-month treatment, the effective rates on the observation and the control sides were comparable. The incidence of adverse reactions was similar between the two instruments. Thus, the UI04 IPL and BBL IPL hair removal device exhibit similar efficacy and safety for hair removal.This study confirms that the efficacy and safety of the UI04 IPL as an at-home hair removal device is similar to that of IPL devices, while they are inexpensive, easy to operate, portable, and can be used as an alternative treatment for hair removal. Trial registration 20210454.
尽管市面上有许多家用强脉冲光（IPL）设备可用于脱毛，但这些设备与医院使用的IPL设备相比，其疗效和安全性是否相当尚不清楚。因此，我们在此比较了一款家用UI04 IPL冰点脱毛设备和一款宽谱光（BBL）强脉冲光脱毛设备的脱毛疗效和安全性。共有84名参与者从我们的门诊招募。在每位参与者身上，腋窝、小腿或前臂的右侧和左侧被随机分配到使用UI04 IPL脱毛设备治疗的观察组或使用BBL设备治疗的对照组，为期3个月，并随访3个月。我们的结果显示，84名患者中有78名（87.6%）完成了研究。治疗1个月后，观察组的脱毛有效率显著高于对照组（P = 0.001）。治疗3个月后，观察组和对照组的有效率相当。两种仪器的不良反应发生率相似。因此，UI04 IPL和BBL IPL脱毛设备在脱毛方面具有相似的疗效和安全性。本研究证实，UI04 IPL作为家用脱毛设备的疗效和安全性与IPL设备相似，同时它们价格低廉、易于操作、便于携带，可作为脱毛的替代治疗方法。试验注册号20210454。
