Babilas Philipp, Schreml Stephan, Szeimies Rolf-Markus, Landthaler Michael
Department of Dermatology, University Hospital Regensburg, 93042 Regensburg, Germany.
Lasers Surg Med. 2010 Feb;42(2):93-104. doi: 10.1002/lsm.20877.
Intense pulsed light (IPL) devices use flashlamps and bandpass filters to emit polychromatic incoherent high-intensity pulsed light of determined wavelength spectrum, fluence, and pulse duration. Similar to lasers, the basic principle of IPL devices is a more or less selective thermal damage of the target. The combination of prescribed wavelengths, fluences, pulse durations, and pulse intervals facilitates the treatment of a wide spectrum of skin conditions.
To summarize the physics of IPL, to provide guidance for the practical use of IPL devices, and to discuss the current literature on IPL in the treatment of unwanted hair growth, vascular lesions, pigmented lesions, acne vulgaris, and photodamaged skin and as a light source for PDT and skin rejuvenation.
A systematic search of several electronic databases, including Medline and PubMed and the authors experience on intense pulsed light.
Numerous trials show the effectiveness and compatibility of IPL devices.
Most comparative trials attest IPLs similar effectiveness to lasers (level of evidence: 2b to 4, depending on the indication). However, large controlled and blinded comparative trials with an extended follow-up period are necessary.
强脉冲光（IPL）设备使用闪光灯和带通滤波器来发射具有特定波长光谱、能量密度和脉冲持续时间的多色非相干高强度脉冲光。与激光类似，IPL设备的基本原理是对目标进行或多或少的选择性热损伤。规定的波长、能量密度、脉冲持续时间和脉冲间隔的组合便于治疗广泛的皮肤疾病。
总结IPL的物理学原理，为IPL设备的实际应用提供指导，并讨论当前关于IPL治疗多毛症、血管病变、色素沉着病变、寻常痤疮和光损伤皮肤以及作为光动力疗法（PDT）和皮肤年轻化光源的文献。
对多个电子数据库进行系统检索，包括Medline和PubMed，并结合作者对强脉冲光的经验。
大量试验表明IPL设备的有效性和兼容性。
大多数比较试验证明IPL与激光具有相似的有效性（证据水平：2b至4，取决于适应证）。然而，需要进行大规模的有对照和盲法的比较试验，并延长随访期。
