Indraprasit S, Sooksriwongse C
Nephron. 1985;40(3):341-3. doi: 10.1159/000183489.
Chlorpromazine added to the dialysate improved the ultrafiltration and increased peritoneal clearances of urea and inulin. These results were postulated to be due to the narrowed stagnant dialysate fluid layer by the surface-active property of chlorpromazine. The study suggested another way to improve large solute (possibly uremic toxin) transport by using substances that facilitate convective transport. Intraperitoneal chlorpromazine increased the peritoneal dialysis efficiency.
向透析液中添加氯丙嗪可改善超滤，并增加尿素和菊粉的腹膜清除率。这些结果被推测是由于氯丙嗪的表面活性特性使停滞的透析液层变窄所致。该研究提出了另一种通过使用促进对流运输的物质来改善大溶质（可能是尿毒症毒素）转运的方法。腹腔内注射氯丙嗪可提高腹膜透析效率。
