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Targeting inflammation to prevent and treat sensorineural hearing loss.

作者信息

Li Ting, Yu Wenting, Lei Wenyang, Zong Shimin, Xiao Hongjun

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.

Institute of Otorhinolaryngology-Head and Neck Surgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.

出版信息

Chin Med J (Engl). 2025 May 20;138(10):1248-1250. doi: 10.1097/CM9.0000000000003506. Epub 2025 Mar 19.

DOI:10.1097/CM9.0000000000003506
PMID:40108775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12091648/
Abstract
摘要

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本文引用的文献

1
AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial.AAV1-hOTOF 基因治疗常染色体隐性遗传性耳聋 9 型：一项单臂试验。
Lancet. 2024 May 25;403(10441):2317-2325. doi: 10.1016/S0140-6736(23)02874-X. Epub 2024 Jan 24.
2
Injury and protection of spiral ganglion neurons.螺旋神经节神经元的损伤与保护。
Chin Med J (Engl). 2024 Mar 20;137(6):651-656. doi: 10.1097/CM9.0000000000002765. Epub 2023 Jul 5.
3
The Stria Vascularis in Mice and Humans Is an Early Site of Age-Related Cochlear Degeneration, Macrophage Dysfunction, and Inflammation.血管纹在小鼠和人类中是与年龄相关的耳蜗退行性变、巨噬细胞功能障碍和炎症的早期部位。
J Neurosci. 2023 Jul 5;43(27):5057-5075. doi: 10.1523/JNEUROSCI.2234-22.2023. Epub 2023 Jun 2.
4
Cytokine Levels in Inner Ear Fluid of Young and Aged Mice as Molecular Biomarkers of Noise-Induced Hearing Loss.青年和老年小鼠内耳液中的细胞因子水平作为噪声性听力损失的分子生物标志物
Front Neurol. 2019 Sep 11;10:977. doi: 10.3389/fneur.2019.00977. eCollection 2019.
5
Chronic inflammation - inflammaging - in the ageing cochlea: A novel target for future presbycusis therapy.慢性炎症-衰老性炎症-衰老耳蜗：未来感音神经性聋治疗的新靶点。
Ageing Res Rev. 2017 Nov;40:142-148. doi: 10.1016/j.arr.2017.10.002. Epub 2017 Oct 7.