Jiang Yuan, Xia Ke-Ke, Lin Zhi-Yuan
Department of Psychiatry, The Seventh People's Hospital of Wenzhou, Wenzhou 325000, Zhejiang Province, China.
General Psychiatry, The Seventh People's Hospital of Wenzhou, Wenzhou 325000, Zhejiang Province, China.
World J Psychiatry. 2025 Mar 19;15(3):100009. doi: 10.5498/wjp.v15.i3.100009.
Depression is one of the most common mental disorders, with high rates of disability, particularly among women.
To explore the effects of suggestion therapy on anxiety, mood, and sleep-quality in middle-aged women with depression treated with escitalopram.
Overall, 102 female patients with depression aged 35-49 years were divided into control and experimental groups. The control group received oral escitalopram therapy, starting at a dose of 5 mg/day, which was gradually increased to 10-20 mg/day after 1 week for a total of 8 weeks. The experimental group received the suggested therapy based on the control group. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Profile of Mood States-Short Form, and Pittsburgh Sleep Quality Index (PSQI) were used to assess depression, anxiety, mood status, and sleep quality.
Before treatment, there were no significant differences in the SDS, SAS, Profile of Mood States, and PSQI scores between the two groups ( > 0.05). After treatment, compared to the control group and baseline, the SDS, SAS, tension-anxiety, depression-dejection, and confusion-bewilderment scores in the experimental group significantly decreased ( < 0.05), whereas sleep efficiency, sleep disturbance, hypnotics, and PSQI scores significantly increased ( < 0.05).
Suggestion therapy combined with escitalopram treatment can reduce the severity of depression and anxiety, change mood status, and improve sleep quality in middle-aged women with depression.
抑郁症是最常见的精神障碍之一,致残率很高,尤其是在女性中。
探讨暗示疗法对接受艾司西酞普兰治疗的中年抑郁症女性患者焦虑、情绪和睡眠质量的影响。
总共102名年龄在35 - 49岁的女性抑郁症患者被分为对照组和实验组。对照组接受口服艾司西酞普兰治疗,起始剂量为5毫克/天,1周后逐渐增加至10 - 20毫克/天,共治疗8周。实验组在对照组基础上接受暗示疗法。采用自评抑郁量表(SDS)、自评焦虑量表(SAS)、简式情绪状态量表和匹兹堡睡眠质量指数(PSQI)评估抑郁、焦虑、情绪状态和睡眠质量。
治疗前,两组的SDS、SAS、情绪状态量表和PSQI评分无显著差异(>0.05)。治疗后,与对照组及基线相比,实验组的SDS、SAS、紧张 - 焦虑、抑郁 - 沮丧和困惑 - 迷茫评分显著降低(<0.05),而睡眠效率、睡眠障碍、催眠药物使用和PSQI评分显著升高(<0.05)。
暗示疗法联合艾司西酞普兰治疗可减轻中年抑郁症女性患者的抑郁和焦虑严重程度,改变情绪状态,改善睡眠质量。