Mondia Mark Willy L, Avila Edward K, Wefel Jeffrey S, Hehn Rachel F, Bowers Alex R, Cox Brian S, Cox Daniel J, Schiff David
Division of Neuro-Oncology, Department of Neurology, University of Virginia, Charlottesville, Virginia, USA.
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Neurooncol Pract. 2024 Dec 6;12(2):183-196. doi: 10.1093/nop/npae119. eCollection 2025 Apr.
Patients with brain tumors and their families often inquire about driving safety. Currently, there is no consensus regarding fitness-to-drive (FTD) for patients with central nervous system tumors. Our paper aims to provide a multi-disciplinary perspective to address this issue.
We performed a literature review for brain tumors and driving. Additionally, we solicited input from experts in tumor-related epilepsy, ophthalmology, neuropsychology, occupational therapy, and driving simulators.
We qualitatively analyzed 14 published articles. FTD determination varies internationally and regionally in most developed nations. Significant motor weakness and major cognitive impairment clearly prevent patients from driving. There are specialized tests for motor, vision, and cognitive correlates important to driving, but driving simulators and on-the-road tests provide the most comprehensive assessments. FTD for patients with seizures is dependent on region-specific laws that take into account the duration of seizure-free intervals and history of motor vehicular crashes.
We recommend a symptom-based approach that highlights the importance of interdisciplinary assessment to ensure that brain tumor patients have the minimum operational skills required to drive. It is crucial to document seizure control, visual acuity impairment, and visual field deficits because these factors usually become the default basis in practice to determine if driving privileges can be maintained. Appropriately, timed assessment of cognitive function may provide pertinent information to determine FTD. Formalized testing with practical driving evaluation may eventually be necessary in patients who have hemiparesis, hemiplegia, hemineglect, homonymous visual field loss, or any form of cognitive dysfunction to determine FTD.
脑肿瘤患者及其家属常常询问驾驶安全性问题。目前,对于中枢神经系统肿瘤患者的驾驶适宜性(FTD)尚无共识。我们的论文旨在提供多学科视角来解决这一问题。
我们对脑肿瘤与驾驶相关文献进行了综述。此外,我们征求了肿瘤相关性癫痫、眼科、神经心理学、职业治疗以及驾驶模拟器等领域专家的意见。
我们对14篇已发表文章进行了定性分析。在大多数发达国家,FTD的判定在国际和地区层面存在差异。明显的运动无力和严重的认知障碍显然会妨碍患者驾驶。对于与驾驶重要相关的运动、视力和认知方面有专门测试,但驾驶模拟器和上路测试能提供最全面的评估。癫痫患者的FTD取决于特定地区的法律,这些法律会考虑无癫痫发作间隔的时长以及机动车碰撞事故史。
我们推荐一种基于症状的方法,强调跨学科评估的重要性,以确保脑肿瘤患者具备驾驶所需的最低操作技能。记录癫痫控制情况、视力损害和视野缺损至关重要,因为在实践中这些因素通常成为确定是否能保留驾驶特权的默认依据。相应地,对认知功能进行定时评估可能会为确定FTD提供相关信息。对于有偏瘫、半身不遂、偏侧忽视、同向性视野缺损或任何形式认知功能障碍的患者,最终可能需要进行正式的实际驾驶评估测试来确定FTD。