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挖掘植物多酚的潜力:提取、抗菌机制及未来应用的进展

Unlocking the potential of plant polyphenols: advances in extraction, antibacterial mechanisms, and future applications.

作者信息

Wang Lei, Li Tingting, Wu Caie, Fan Gongjian, Zhou Dandan, Li Xiaojing

机构信息

Department of Food Science and Technology, College of Light Industry and Food Engineering, Nanjing Forestry University, No.159 Long pan Road, Nanjing, 210037 Jiangsu People's Republic of China.

Co-Innovation Center for the Sustainable Forestry in Southern China, Nanjing Forestry University, No.159 Long pan Road, Nanjing, 210037 Jiangsu People's Republic of China.

出版信息

Food Sci Biotechnol. 2024 Oct 15;34(6):1235-1259. doi: 10.1007/s10068-024-01727-5. eCollection 2025 Apr.

DOI:10.1007/s10068-024-01727-5
PMID:40110409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11914671/
Abstract

Plant polyphenols are widely distributed in most higher plants, garnering significant attention from researchers due to their remarkable antioxidative, antibacterial, anticancer, and anti-radiation properties. They also offer multiple health benefits for various lifestyle-related diseases and oxidative stress. While there has been considerable research on the extraction and antibacterial application of plant polyphenols, developing a rapid and efficient extraction method remains a persistent challenge. Furthermore, the introduction of novel technologies is imperative to enhance the bioavailability of polyphenolic compounds. This comprehensive review synthesizes recent research findings pertaining to the extraction, antibacterial mechanisms, and applications of plant polyphenols. This research highlights the prevalent issues of low extraction rates of plant polyphenols and the ambiguous antibacterial mechanisms in current research. To address these challenges, this research proposes innovative directions for improving extraction technology and expanding antibacterial applications. Additionally, this review outlines promising future research avenues within the realm of plant polyphenols.

摘要

植物多酚广泛分布于大多数高等植物中,因其具有显著的抗氧化、抗菌、抗癌和抗辐射特性而备受研究人员关注。它们还对各种与生活方式相关的疾病和氧化应激具有多种健康益处。虽然对植物多酚的提取和抗菌应用已有大量研究,但开发一种快速高效的提取方法仍然是一个长期挑战。此外,引入新技术对于提高多酚类化合物的生物利用度至关重要。这篇综述综合了有关植物多酚提取、抗菌机制及应用的最新研究成果。该研究突出了当前研究中植物多酚提取率低和抗菌机制不明确等普遍问题。为应对这些挑战,本研究提出了改进提取技术和拓展抗菌应用的创新方向。此外,本综述还概述了植物多酚领域未来有前景的研究途径。

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本文引用的文献

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Applications of magnetic solid-phase extraction in the sample preparation of natural product analysis (2020-2023).磁性固相萃取在天然产物分析样品制备中的应用(2020 - 2023年)
J Sep Sci. 2024 Jun;47(11):e2400082. doi: 10.1002/jssc.202400082.
2
Deep eutectic solvents for the extraction of polyphenols from food plants.用于从食用植物中提取多酚的深共熔溶剂。
Food Chem. 2024 Jun 30;444:138629. doi: 10.1016/j.foodchem.2024.138629. Epub 2024 Feb 3.
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Polyphenols in Plants: Structure, Biosynthesis, Abiotic Stress Regulation, and Practical Applications (Review).植物中的多酚:结构、生物合成、非生物胁迫调控及实际应用(综述)
Int J Mol Sci. 2023 Sep 9;24(18):13874. doi: 10.3390/ijms241813874.
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Inhibition of Cancer Development by Natural Plant Polyphenols: Molecular Mechanisms.天然植物多酚抑制癌症发生的分子机制。
Int J Mol Sci. 2023 Jun 26;24(13):10663. doi: 10.3390/ijms241310663.
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Antioxidative polyphenols attenuate pyocyanin-induced ROS production in neuronal HT22 cell lines.抗氧化多酚可减轻绿脓菌素诱导的神经元HT22细胞系中的活性氧生成。
RSC Adv. 2023 Jun 28;13(28):19477-19484. doi: 10.1039/d3ra02943c. eCollection 2023 Jun 22.
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Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.采用单价多酚通过 FeOOH 辅助制备金属-多酚网络抗肿瘤试剂。
J Control Release. 2023 Jun;358:612-625. doi: 10.1016/j.jconrel.2023.05.020. Epub 2023 May 19.
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UPLC‒ESI‒MS/MS profiling of active polyphenolics in Morinda coreia leaf extract and in vitro antioxidant and antibacterial activity.UPLC-ESI-MS/MS 分析桑枝提取物中活性多酚的成分及体外抗氧化和抗菌活性。
Chemosphere. 2023 May;323:138179. doi: 10.1016/j.chemosphere.2023.138179. Epub 2023 Feb 25.
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The Effect of Extraction Methods on Phytochemicals and Biological Activities of Green Coffee Beans Extracts.提取方法对生咖啡豆提取物的植物化学成分和生物活性的影响。
Plants (Basel). 2023 Feb 6;12(4):712. doi: 10.3390/plants12040712.
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Plant-Derived Polyphenol and LL-37 Peptide-Modified Nanofibrous Scaffolds for Promotion of Antibacterial Activity, Anti-Inflammation, and Type-H Vascularized Bone Regeneration.植物源多酚和 LL-37 肽修饰的纳米纤维支架促进抗菌活性、抗炎和 H 型血管化骨再生。
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High-efficiency novel extraction process of target polyphenols using enzymes in hydroalcoholic media.高效新型提取工艺:在醇水介质中利用酶提取目标多酚。
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