Patel C, Lloyd R S, Holdstock G
Postgrad Med J. 1985 Jun;61(716):509-10. doi: 10.1136/pgmj.61.716.509.
An autoantibody screen is often requested in patients with non-specific symptoms such as pyrexia of unknown origin. However, in a survey of 100 consecutive requests for this investigation in such patients only one patient was encountered in whom the investigation led to a positive diagnosis at an estimated cost of pound 2500. These requests accounted for 5% of the total workload. These observations reaffirm that this should remain a second line investigation and should be deferred until more likely diagnoses have been excluded.
对于有不明原因发热等非特异性症状的患者，常常会要求进行自身抗体筛查。然而，在对这类患者连续100次此项检查申请的调查中，仅发现1例患者通过该项检查得出了阳性诊断，估计费用为2500英镑。这些申请占总工作量的5%。这些观察结果再次证实，这应仍是二线检查，应推迟到排除更可能的诊断之后。
