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基层医疗环境中老年患者的中风患病率及相关危险因素:一项回顾性队列研究。

Prevalence of stroke and associated risk factors among elderly patients in a primary care setting: A retrospective cohort study.

作者信息

Alabduljabbar Khaled, Elabd Kossay, Alsaif Abdulaziz, Basudan Loay

机构信息

Department of Family Medicine and Polyclinics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Family and Community Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

出版信息

J Family Med Prim Care. 2025 Feb;14(2):749-756. doi: 10.4103/jfmpc.jfmpc_1569_24. Epub 2025 Feb 21.

DOI:10.4103/jfmpc.jfmpc_1569_24
PMID:40115564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11922352/
Abstract

BACKGROUND

Stroke is a major health concern worldwide, with significant morbidity and mortality. This study aims to retrospectively analyze the prevalence and risk factors associated with stroke in a primary care setting in Riyadh, Saudi Arabia.

METHODS

A retrospective cohort study was conducted at the Family Medicine and Polyclinics, King Faisal Specialist Hospital and Research Centre in Riyadh. Data were collected from patients aged 50 years and older who visited the clinic between January 1, 2021, and December 31, 2022. Stroke diagnoses were determined using ICD-10 codes, and data on demographic variables and stroke risk factors were extracted from medical records. Statistical analyses included Chi-square or Fisher's Exact tests, Mann-Whitney U test, and logistic regression analysis.

RESULTS

Out of 2034 patients, 36 (1.8%) were diagnosed with stroke, predominantly ischemic (91.7%). Significant correlations with stroke occurrence included advanced age, male gender, family history of stroke, and comorbidities such as hypertension, transient ischemic attack, ischemic heart disease, brain aneurysm, and carotid artery disease. Multivariable analysis identified older age (≥80 years, OR = 8.949, = 0.013), male gender (OR = 5.980, = 0.010), underweight status (OR = 50.873, = 0.005), family history of stroke (OR = 12.603, = 0.040), and hypertension (OR = 7.984, = 0.009) as significant risk factors for stroke.

CONCLUSION

Stroke prevalence in the sampled population was 18 per 100,000 individuals, with advanced age, male gender, and hypertension identified as significant risk factors. These findings highlight the need for targeted preventive strategies and further prospective research to establish causal relationships and improve stroke management in Saudi Arabia.

摘要

背景

中风是全球主要的健康问题,具有较高的发病率和死亡率。本研究旨在回顾性分析沙特阿拉伯利雅得初级保健机构中中风的患病率及相关危险因素。

方法

在利雅得的法赫德国王专科医院及研究中心的家庭医学与综合诊所进行了一项回顾性队列研究。收集了2021年1月1日至2022年12月31日期间就诊的50岁及以上患者的数据。使用国际疾病分类第十版(ICD - 10)编码确定中风诊断,并从病历中提取人口统计学变量和中风危险因素的数据。统计分析包括卡方检验或费舍尔精确检验、曼 - 惠特尼U检验和逻辑回归分析。

结果

在2034名患者中,36名(1.8%)被诊断为中风,主要为缺血性中风(91.7%)。与中风发生显著相关的因素包括高龄、男性、中风家族史以及高血压、短暂性脑缺血发作、缺血性心脏病、脑动脉瘤和颈动脉疾病等合并症。多变量分析确定高龄(≥80岁,OR = 8.949,P = 0.013)、男性(OR = 5.980,P = 0.010)、体重过轻状态(OR = 50.873,P = 0.005)、中风家族史(OR = 12.603,P = 0.040)和高血压(OR = 7.984,P = 0.009)是中风的显著危险因素。

结论

抽样人群中的中风患病率为每10万人中有18例,高龄、男性和高血压被确定为显著危险因素。这些发现凸显了在沙特阿拉伯制定针对性预防策略以及进一步开展前瞻性研究以建立因果关系并改善中风管理的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1af/11922352/a1c31ef9e65f/JFMPC-14-749-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1af/11922352/a1c31ef9e65f/JFMPC-14-749-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1af/11922352/a1c31ef9e65f/JFMPC-14-749-g001.jpg

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本文引用的文献

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Saudi Med J. 2023 Oct;44(10):951-964. doi: 10.15537/smj.2023.44.10.20230178.
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Diabetes and Stroke: What Are the Connections?糖尿病与中风:有何关联?
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Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies.中国卒中危险因素的识别:前瞻性队列研究的Meta分析
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