Zhang Lianmei, Jin Xinglin
Int J Clin Pharmacol Ther. 2025 May;63(5):208-216. doi: 10.5414/CP204715.
The high incidence of malignant tumors continues to pose a significant threat to public health. In recent years, there have been notable advancements in tumor treatment methods, leading to substantial changes in the concepts and clinical approaches to treatment. The primary clinical methods for treating malignant tumors currently include surgical resection, radiation therapy, and chemotherapy. Among these, chemotherapy is one of the most crucial and comprehensive treatment strategies. The rapid progress in nanoscience has fostered the development of nanocarrier compounds and their clinical applications in disease treatment. Notably, nanomedicines, including goserelin sustained-release implants, doxorubicin liposomes, albumin-bound paclitaxel, and paclitaxel liposomes, have been effectively utilized in tumor treatment in China [
恶性肿瘤的高发病率持续对公众健康构成重大威胁。近年来,肿瘤治疗方法取得了显著进展,导致治疗理念和临床方法发生了重大变化。目前治疗恶性肿瘤的主要临床方法包括手术切除、放射治疗和化疗。其中,化疗是最关键和全面的治疗策略之一。纳米科学的迅速发展推动了纳米载体化合物的开发及其在疾病治疗中的临床应用。值得注意的是,包括戈舍瑞林缓释植入剂、阿霉素脂质体、白蛋白结合型紫杉醇和紫杉醇脂质体在内的纳米药物已在中国的肿瘤治疗中得到有效应用[