Kraake Sophia, Luppa Melanie, Saur Dorothee, Dietzel Jens, Bach Jan-Philipp, Riedel-Heller Steffi G, Stein Janine
Institute of Social Medicine, Occupational Health and Public Health, Medical Faculty, University of Leipzig, Leipzig, Leipzig, Germany.
Department of Neurology, Neuroimaging Laboratory, University of Leipzig, Leipzig, Leipzig, Germany.
J Alzheimers Dis. 2025 May;105(1):77-89. doi: 10.1177/13872877251326029. Epub 2025 Mar 21.
BackgroundChanges in social functioning may be a significant parameter for the early detection of Alzheimer's disease (AD). Currently, research on social functioning in AD across the entire spectrum of the disease is lacking.ObjectiveThe aim of this study was to describe the social functioning of persons with AD at each stage of the disease and to investigate how impaired social functioning affects caregiver burden.MethodsCross-sectional data was derived from memory clinics across Germany as part of the pilot study "Social functioning in individuals with AD and the situation of caregivers". A total of N = 87 relatives providing care for individuals with mild (n = 20), moderate (n = 40), and severe (n = 23) AD were included. Social functioning of individuals with AD was measured via the caregiver-rated German version of the Social Functioning in Dementia Scale (SF-DEM); caregiver burden was assessed using the Zarit Caregiver Burden Interview (ZBI-12). Differences between mild, moderate, and severe AD in terms of sociodemographic characteristics and the level of social functioning were examined. A robust linear regression analysis was conducted to examine the association between social functioning and caregiver burden.ResultsSocial functioning was lower in moderate and severe AD than in mild AD. Higher levels of social functioning were associated with less caregiver burden.ConclusionsThis study highlights the importance of integrating social functioning assessments into clinical practice for improving the early detection, diagnosis and interventions for AD. Early interventions to enhance social functioning may diminish caregiver burden.
背景
社会功能的变化可能是早期发现阿尔茨海默病(AD)的一个重要参数。目前,缺乏针对AD全病程社会功能的研究。
目的
本研究的目的是描述AD患者在疾病各阶段的社会功能,并调查社会功能受损如何影响照料者负担。
方法
作为“AD患者的社会功能与照料者状况”试点研究的一部分,横断面数据来自德国各地的记忆门诊。共纳入了N = 87名照料轻度(n = 20)、中度(n = 40)和重度(n = 23)AD患者的亲属。AD患者的社会功能通过照料者评定的德语版痴呆症社会功能量表(SF-DEM)进行测量;照料者负担使用扎里特照料者负担访谈量表(ZBI-12)进行评估。研究了轻度、中度和重度AD在社会人口学特征和社会功能水平方面的差异。进行了稳健线性回归分析,以检验社会功能与照料者负担之间的关联。
结果
中度和重度AD患者的社会功能低于轻度AD患者。社会功能水平越高,照料者负担越小。
结论
本研究强调了将社会功能评估纳入临床实践对于改善AD的早期发现、诊断和干预的重要性。增强社会功能的早期干预可能会减轻照料者负担。