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移民中丙型肝炎的患病率:一项系统评价和荟萃分析。

Prevalence of Hepatitis C Among Migrants: A Systematic Review and Meta-Analysis.

作者信息

Sun Jiajun, Kelly Matthew, Tsheten Tsheten, Pourmarzi Davoud

机构信息

National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia.

出版信息

J Viral Hepat. 2025 Apr;32(4):e70025. doi: 10.1111/jvh.70025.

Abstract

The World Health Organisation has targeted the Hepatitis C virus (HCV) to be eliminated as a public health threat by 2030. Equitable access to HCV testing and treatment services is important in achieving this goal. Migrants often face barriers to accessing health services, and understanding HCV prevalence among this population can support planning for elimination. This systematic review aimed to estimate HCV prevalence among migrants residing in high-income countries with low/intermediate HCV prevalence. Scopus, PubMed, PsycINFO and Cochrane Library were searched for peer-reviewed articles published in English between 2015 and 2024. The studies' quality was assessed using The Joanna Briggs Institute (JBI) Critical Appraisal Tools. A proportional meta-analysis was used to estimate HCV prevalence. Thirty-seven studies were included in this review. Seventeen studies included both people < 18 and ≥ 18 years old, 16 studies only included people ≥ 18 years old, and three studies included people aged 18 and younger. The pooled prevalence of HCV antibody (anti-HCV) and RNA (HCV-RNA) were 1.5% (95% CI, 1.1%-2.0%) and 0.6% (95% CI, 0.4%-0.9%), respectively. The prevalence of anti-HCV was higher among males (1.9%) than females (0.6%). Among refugees and asylum seekers, the prevalence of anti-HCV and HCV-RNA were 1.4% and 0.7%, respectively. The prevalence of HCV among migrants is comparable with that among the general population of the destination countries. Given the barriers migrants, especially refugees and asylum seekers, face in accessing health services, their access to HCV information, testing and treatment should be facilitated.

摘要

世界卫生组织的目标是到2030年消除丙型肝炎病毒(HCV)对公共卫生的威胁。公平获得HCV检测和治疗服务对于实现这一目标至关重要。移民在获得医疗服务方面往往面临障碍,了解这一人群中的HCV流行情况有助于支持消除计划的制定。本系统评价旨在估计居住在HCV流行率低/中等的高收入国家的移民中的HCV流行率。在Scopus、PubMed、PsycINFO和Cochrane图书馆中检索了2015年至2024年期间以英文发表的同行评审文章。使用乔安娜·布里格斯研究所(JBI)的批判性评价工具对研究质量进行评估。采用比例荟萃分析来估计HCV流行率。本评价纳入了37项研究。17项研究纳入了年龄<18岁和≥18岁的人群,16项研究仅纳入了≥18岁的人群,3项研究纳入了18岁及以下的人群。HCV抗体(抗-HCV)和RNA(HCV-RNA)的合并流行率分别为1.5%(95%CI,1.1%-2.0%)和0.6%(95%CI,0.4%-0.9%)。男性抗-HCV流行率(1.9%)高于女性(0.6%)。在难民和寻求庇护者中,抗-HCV和HCV-RNA的流行率分别为1.4%和0.7%。移民中的HCV流行率与目的地国家普通人群中的流行率相当。鉴于移民,尤其是难民和寻求庇护者在获得医疗服务方面面临的障碍,应促进他们获得HCV信息、检测和治疗。

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