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腹腔镜下单吻合十二指肠-回肠旁路术联合袖状胃切除术的早期结果:来自波兰一家减肥中心的病例系列研究

Early results of laparoscopic single‑anastomosis duodeno‑ileal bypass with sleeve gastrectomy: a case series from a single Polish bariatric center.

作者信息

Wityk Mateusz, Bobowicz Maciej, Pryt Mateusz, Dowgiałło-Gornowicz Natalia

机构信息

Department of General and Oncological Surgery, Regional Health Centre, Lubin, Poland.

Department of Radiology, Medical University of Gdansk, Gdańsk, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2024 Nov 19;19(4):460-464. doi: 10.20452/wiitm.2024.17912. eCollection 2024 Dec 27.

Abstract

INTRODUCTION

The obesity epidemic has led to an increased prevalence of related conditions, such as type 2 diabetes (T2D) and hypertension. While laparoscopic sleeve gastrectomy is the most common metabolic bariatric surgery, up to 50% of patients may require revisional procedures due to weight regain or comorbidity recurrence. Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is emerging as an effective treatment option with promising short-term outcomes.

AIM

This study aimed to present the outcomes of patients who underwent SADI-S or revisional SADI.

MATERIALS AND METHODS

This retrospective, single-center cohort study included 12 patients who underwent SADI-S or SADI between February 2023 and March 2024. The patients were assessed for percentage of total weight loss (%TWL), remission of T2D and hypertension, length of hospital stay, operative time, and complications. All outcomes were reported according to the American Society for Metabolic and Bariatric Surgery standards.

RESULTS

A total of 9 patients underwent primary SADI-S and 3 underwent revisional SADI. The mean (SD) %TWL was 27.9% (4.3%) at 6 months and 31.1% (5.9%) at 12 months after SADI and 21.2% (15.2%) and 14% (7.5%), respectively, after SADI-S. The mean (SD) preoperative body mass index was 42 (5.5) kg/m2 in the primary SADI-S group and 42.4 (9.3) kg/m2 in the revisional SADI group, and the mean (SD) follow-up was 10.1 (3.4) months. Full remission of T2D and hypertension was achieved in all patients within 6 months of surgery. There were no major complications, except for 1 case of intraoperative conversion to one-anastomosis gastric bypass.

CONCLUSIONS

SADI-S is associated with significant weight loss and comorbidity resolution with a low complication rate, though larger studies are needed for further validation of these results.

摘要

引言

肥胖流行导致2型糖尿病(T2D)和高血压等相关疾病的患病率上升。虽然腹腔镜袖状胃切除术是最常见的代谢性减肥手术,但高达50%的患者可能因体重反弹或合并症复发而需要进行修正手术。单吻合口十二指肠回肠旁路术联合袖状胃切除术(SADI-S)正逐渐成为一种有效的治疗选择,短期疗效良好。

目的

本研究旨在介绍接受SADI-S或修正性SADI手术患者的治疗结果。

材料与方法

这项回顾性单中心队列研究纳入了2023年2月至2024年3月期间接受SADI-S或SADI手术的12例患者。评估患者的总体重减轻百分比(%TWL)、T2D和高血压的缓解情况、住院时间、手术时间及并发症。所有结果均按照美国代谢与减肥外科学会的标准报告。

结果

共有9例患者接受了初次SADI-S手术,3例接受了修正性SADI手术。SADI术后6个月和12个月时,平均(标准差)%TWL分别为27.9%(4.3%)和31.1%(5.9%);SADI-S术后分别为21.2%(15.2%)和14%(7.5%)。初次SADI-S组术前平均(标准差)体重指数为42(5.5)kg/m²,修正性SADI组为42.4(9.3)kg/m²,平均(标准差)随访时间为10.1(3.4)个月。所有患者在术后6个月内实现了T2D和高血压的完全缓解。除1例术中转为单吻合口胃旁路术外,无重大并发症发生。

结论

SADI-S与显著的体重减轻和合并症缓解相关,并发症发生率低,不过需要更大规模的研究来进一步验证这些结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee4b/11927553/7b566be9b6ad/vomt-19-04-17912-f1.jpg

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