对于感染性休克患儿，是否应采用宽松液体疗法（与限制性液体疗法相比）？答案是肯定的。 - Suppr

Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be Used in Children with Septic Shock? Yes.

作者信息

Nallasamy Karthi, Venkateshwaralu Saicharan

机构信息

Pediatric Critical Care Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

出版信息

Indian Pediatr. 2025 Mar;62(3):233-235. doi: 10.1007/s13312-025-00013-9.

DOI:10.1007/s13312-025-00013-9

PMID:40126832

Abstract

摘要

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本文引用的文献

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension.

N Engl J Med. 2023 Feb 9;388(6):499-510. doi: 10.1056/NEJMoa2212663. Epub 2023 Jan 21.

Point-of-care ultrasonography to predict fluid responsiveness in children: A systematic review and meta-analysis.

Paediatr Anaesth. 2023 Jan;33(1):24-37. doi: 10.1111/pan.14574. Epub 2022 Oct 19.

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.

Pediatr Crit Care Med. 2020 Feb;21(2):e52-e106. doi: 10.1097/PCC.0000000000002198.

Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE.

Crit Care. 2016 Jul 1;20(1):160. doi: 10.1186/s13054-016-1288-3.

Four phases of intravenous fluid therapy: a conceptual model.

Br J Anaesth. 2014 Nov;113(5):740-7. doi: 10.1093/bja/aeu300. Epub 2014 Sep 9.

The role of venous return in critical illness and shock-part I: physiology.

Crit Care Med. 2013 Jan;41(1):255-62. doi: 10.1097/CCM.0b013e3182772ab6.

Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy.

Br J Anaesth. 2012 Mar;108(3):384-94. doi: 10.1093/bja/aer515. Epub 2012 Jan 29.

Mortality after fluid bolus in African children with severe infection.

N Engl J Med. 2011 Jun 30;364(26):2483-95. doi: 10.1056/NEJMoa1101549. Epub 2011 May 26.

Effects of fluids on microvascular perfusion in patients with severe sepsis.

Intensive Care Med. 2010 Jun;36(6):949-55. doi: 10.1007/s00134-010-1843-3. Epub 2010 Mar 11.

Early goal-directed therapy in the treatment of severe sepsis and septic shock.

N Engl J Med. 2001 Nov 8;345(19):1368-77. doi: 10.1056/NEJMoa010307.

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Should Liberal Fluid Therapy (Compared to Restrictive Fluid Therapy) be Used in Children with Septic Shock? Yes.

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