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[犬嗅神经上皮瘤所证实的原发性嗅黏膜肿瘤的诊断]

[The diagnosis of primary olfactory mucosa neoplasms demonstrated by an esthesioneuroepthelioma in the dog].

作者信息

Dahme E, Bilzer T, Mannl A

出版信息

Tierarztl Prax Suppl. 1985;1:112-22.

PMID:4012772
Abstract

In context with the first light and electron microscopic description of a spontaneous esthesioneuroepithelioma in a dog (10 year old female Labrador) general morpho- and etiopathogenetic problems concerning olfactory neoplasias were discussed. Because of its specific location and growth pattern, especially the development of true rosettes and pseudo-rosettes, the tumor was evaluated light microscopically as an esthesioneurogeneic one. The final classification was based upon ultrastructural peculiarities, as occurrence of ciliar structures, characteristic intercellular junctions, and the - although rare - appearance of dense cored vesicles.

摘要

结合对一只狗(10岁雌性拉布拉多犬)自发性嗅神经上皮瘤的首次光镜和电镜描述,讨论了嗅觉肿瘤相关的一般形态学和病因学问题。由于其特殊的位置和生长模式,特别是真性菊形团和假性菊形团的形成,该肿瘤在光镜下被评估为嗅神经源性肿瘤。最终分类基于超微结构特征,如纤毛结构的出现、特征性的细胞间连接以及尽管罕见但出现的致密核心小泡。

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